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一项随机对照试验的研究方案,旨在研究基于社区的力量训练计划是否能提高患有唐氏综合征的年轻成年人的工作任务表现。

A study protocol of a randomised controlled trial to investigate if a community based strength training programme improves work task performance in young adults with Down syndrome.

机构信息

School of Physiotherapy, La Trobe University, Victoria, Australia.

出版信息

BMC Pediatr. 2010 Mar 25;10:17. doi: 10.1186/1471-2431-10-17.

DOI:10.1186/1471-2431-10-17
PMID:20334692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2858133/
Abstract

BACKGROUND

Muscle strength is important for young people with Down syndrome as they make the transition to adulthood, because their workplace activities typically emphasise physical rather than cognitive skills. Muscle strength is reduced up to 50% in people with Down syndrome compared to their peers without disability. Progressive resistance training improves muscle strength and endurance in people with Down syndrome. However, there is no evidence on whether it has an effect on work task performance or physical activity levels. The aim of this study is to investigate if a student-led community-based progressive resistance training programme can improve these outcomes in adolescents and young adults with Down syndrome.

METHODS

A randomised controlled trial will compare progressive resistance training with a control group undertaking a social programme. Seventy adolescents and young adults with Down syndrome aged 14-22 years and mild to moderate intellectual disability will be randomly allocated to the intervention or control group using a concealed method. The intervention group will complete a 10-week, twice a week, student-led progressive resistance training programme at a local community gymnasium. The student mentors will be undergraduate physiotherapy students. The control group will complete an arts/social programme with a student mentor once a week for 90 minutes also for 10 weeks to control for the social aspect of the intervention. Work task performance (box stacking, pail carry), muscle strength (1 repetition maximum for chest and leg press) and physical activity (frequency, duration, intensity over 7-days) will be assessed at baseline (Week 0), following the intervention (Week 11), and at 3 months post intervention (Week 24) by an assessor blind to group allocation. Data will be analysed using ANCOVA with baseline measures as covariates.

DISCUSSION

This paper outlines the study protocol for a randomised controlled trial on the effects of progressive resistance training on work task performance and physical activity for adolescents and young adults with Down syndrome. The intervention addresses the impairment of muscle weakness which may improve work task performance and help to increase physical activity levels.

CLINICAL TRIAL REGISTRATION NUMBER

Australian New Zealand Clinical Trials Registry ACTRN12609000938202.

摘要

背景

对于患有唐氏综合征的年轻人来说,肌肉力量很重要,因为他们正逐渐成年,而他们的工作场所活动通常强调体力而非认知技能。与没有残疾的同龄人相比,唐氏综合征患者的肌肉力量降低了多达 50%。渐进式抗阻训练可提高唐氏综合征患者的肌肉力量和耐力。然而,目前尚无证据表明它对工作任务表现或身体活动水平有影响。本研究旨在探讨学生主导的基于社区的渐进式抗阻训练计划是否可以改善唐氏综合征青少年和年轻人的这些结果。

方法

这是一项随机对照试验,将比较渐进式抗阻训练与对照组(参加社交项目)的效果。将 70 名 14-22 岁、轻度至中度智力障碍的唐氏综合征青少年和年轻人随机分配到干预组或对照组,采用隐蔽方法。干预组将在当地社区健身房完成 10 周、每周 2 次的学生主导的渐进式抗阻训练计划。学生导师将是本科物理治疗专业的学生。对照组将每周与学生导师一起参加 90 分钟的艺术/社交课程,同样持续 10 周,以控制干预的社交方面。工作任务表现(装盒、提桶)、肌肉力量(1 次重复最大胸推和腿推)和身体活动(7 天内的频率、持续时间、强度)将在基线(第 0 周)、干预后(第 11 周)和干预后 3 个月(第 24 周)由对分组分配不知情的评估者进行评估。数据分析将使用协方差分析,以基线测量值为协变量。

讨论

本文概述了一项关于渐进式抗阻训练对唐氏综合征青少年和年轻人工作任务表现和身体活动影响的随机对照试验研究方案。该干预措施针对肌肉无力的损害,这可能改善工作任务表现,并有助于提高身体活动水平。

临床试验注册号

澳大利亚和新西兰临床试验注册中心 ACTRN12609000938202。

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