Division of Biotechnology, Graduate School, Chiang Mai University, Chiang Mai, 50200, Thailand.
Molecules. 2010 Mar 9;15(3):1453-65. doi: 10.3390/molecules15031453.
Nephelium lappaceum is a tropical fruit whose peel possesses antioxidant properties. Experiments on the isolation and identification of the active constituents were conducted, and on their antioxidant activity using a lipid peroxidation inhibition assay. The methanolic extract of N. lappaceum peels exhibited strong antioxidant properties. Sephadex LH-20 chromatography was utilized in the isolation of each constituent and the antioxidant properties of each was studied. The isolated compounds were identified as ellagic acid (EA) (1), corilagin (2) and geraniin (3). These compounds accounted for 69.3% of methanolic extract, with geraniin (56.8%) as the major component, and exhibited much greater antioxidant activities than BHT in both lipid peroxidation (77-186 fold) and DPPH* (42-87 fold) assays. The results suggest that the isolated ellagitannins, as the principal components of rambutan peels, could be further utilized as both a medicine and in the food industry.
莲雾是一种热带水果，其果皮具有抗氧化特性。我们进行了分离和鉴定活性成分的实验，并使用脂质过氧化抑制测定法研究了它们的抗氧化活性。莲雾果皮的甲醇提取物表现出很强的抗氧化活性。我们利用 Sephadex LH-20 层析法分离各个成分，并研究了每个成分的抗氧化活性。分离得到的化合物被鉴定为鞣花酸（EA）（1）、柯里拉京（2）和石榴宁（3）。这些化合物占甲醇提取物的 69.3%，其中石榴宁（56.8%）是主要成分，在脂质过氧化（77-186 倍）和 DPPH*（42-87 倍）测定中，它们的抗氧化活性均明显强于 BHT。结果表明，作为莲雾果皮主要成分的鞣花单宁，可进一步作为药物和食品工业的原料加以利用。
