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探讨银屑病患者心血管及其他疾病相关风险因素之间的关系:整个医学界需要增强相关认识。

Exploring the association between cardiovascular and other disease-related risk factors in the psoriasis population: the need for increased understanding across the medical community.

机构信息

Psoriasis Research Unit, Baylor Research Unit, Dallas, TX, USA.

出版信息

J Eur Acad Dermatol Venereol. 2010 Dec;24(12):1371-7. doi: 10.1111/j.1468-3083.2010.03656.x.

DOI:10.1111/j.1468-3083.2010.03656.x
PMID:20384692
Abstract

There is abundant and accumulating evidence on the classification of psoriasis as a systemic disease that exhibits a host of co-morbidities. As a consequence, the second Interdisciplinary Conference on Co-morbidities and Lifestyle Modification, convened by the International Psoriasis Council, has concluded that specialist physicians, primary care physicians and dermatologists are faced with an opportunity to impact, not just psoriasis disease understanding and management, but overall patient well-being. The conference panel was represented by the disciplines of dermatology, cardiology, rheumatology, epidemiology, endocrinology, hepatology and gastroenterology, and medical specialists with particular expertise in obesity, diabetes mellitus, inflammation and genetics. The multiple co-morbidities associated with psoriasis were reviewed with a view to identify possible mechanisms linking psoriatic disease with obesity, metabolic syndrome, diabetes, cardiovascular disease and non-alcoholic fatty liver disease. Consensus was established on the association of psoriasis with other co-morbidities and disease states. Consequently, there is a significant opportunity for specialist and primary care physicians to collaborate with dermatologists in the management of the overall health of psoriasis patients. First, there is an important need for physicians to routinely screen psoriasis patients for the multiple susceptibility risk factors and co-morbidities associated with psoriasis. Second, the design and implementation of lifestyle modification plans including exercise, diet and the limitation of alcohol and tobacco intake, will not only benefit their general medical health but also their psoriasis.

摘要

有大量证据表明,银屑病是一种全身性疾病,会出现多种合并症。因此,国际银屑病理事会召集的第二次共病和生活方式改变跨学科会议得出结论,专科医生、初级保健医生和皮肤科医生有机会不仅影响对银屑病疾病的理解和管理,而且影响整体患者的健康。会议小组由皮肤科、心脏病学、风湿病学、流行病学、内分泌学、肝脏病学和胃肠病学等学科以及在肥胖症、糖尿病、炎症和遗传学方面具有特定专长的医学专家组成。审查了与银屑病相关的多种合并症,以确定将银屑病疾病与肥胖症、代谢综合征、糖尿病、心血管疾病和非酒精性脂肪性肝病联系起来的可能机制。会议就银屑病与其他合并症和疾病状态的关联达成了共识。因此,专科医生和初级保健医生有机会与皮肤科医生合作,共同管理银屑病患者的整体健康。首先,医生有重要的需要定期对银屑病患者进行筛查,以发现与银屑病相关的多种易感风险因素和合并症。其次,设计和实施生活方式改变计划,包括运动、饮食以及限制酒精和烟草摄入,不仅将有益于他们的一般医疗健康,也有益于他们的银屑病。

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1
Exploring the association between cardiovascular and other disease-related risk factors in the psoriasis population: the need for increased understanding across the medical community.探讨银屑病患者心血管及其他疾病相关风险因素之间的关系:整个医学界需要增强相关认识。
J Eur Acad Dermatol Venereol. 2010 Dec;24(12):1371-7. doi: 10.1111/j.1468-3083.2010.03656.x.
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Obesity in psoriasis: the metabolic, clinical and therapeutic implications. Report of an interdisciplinary conference and review.银屑病中的肥胖:代谢、临床及治疗意义。跨学科会议报告与综述
Br J Dermatol. 2007 Oct;157(4):649-55. doi: 10.1111/j.1365-2133.2007.08068.x. Epub 2007 Jul 11.
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The concept of psoriasis as a systemic inflammation: implications for disease management.银屑病作为一种系统性炎症的概念:对疾病管理的影响。
J Eur Acad Dermatol Venereol. 2012 Mar;26 Suppl 2:3-11. doi: 10.1111/j.1468-3083.2011.04410.x.
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Comorbidities in patients with psoriasis.银屑病患者的合并症。
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Cardiovascular health for patients with psoriasis: a précis for front-line clinicians.银屑病患者的心血管健康:一线临床医生概述
Ostomy Wound Manage. 2009 May 1;55(5):38-47.
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Research in practice: the systemic aspects of psoriasis.实践中的研究:银屑病的系统方面
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Psoriasis: an opportunity to identify cardiovascular risk.银屑病:识别心血管风险的契机。
Br J Dermatol. 2009 Jan;160(1):1-7. doi: 10.1111/j.1365-2133.2008.08874.x. Epub 2008 Oct 25.
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Cardiovascular morbidity in psoriasis: epidemiology, pathomechanisms, and clinical consequences.银屑病中的心血管疾病:流行病学、发病机制及临床后果
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Psoriasis, the liver, and the gastrointestinal tract.银屑病、肝脏与胃肠道。
Dermatol Ther. 2010 Mar-Apr;23(2):155-9. doi: 10.1111/j.1529-8019.2010.01310.x.
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Psoriasis: cardiovascular risk factors and other disease comorbidities.银屑病:心血管危险因素及其他疾病合并症
J Drugs Dermatol. 2008 Apr;7(4):373-7.

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