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Case Rep Med. 2010;2010:313514. doi: 10.1155/2010/313514. Epub 2010 Apr 8.
2
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本文引用的文献

1
Isolation and identification of methylobacterium species from the tap water in hospitals in Japan and their antibiotic susceptibility.
Microbiol Immunol. 2006;50(1):11-7. doi: 10.1111/j.1348-0421.2006.tb03765.x.
2
Methylobacterium hispanicum sp. nov. and Methylobacterium aquaticum sp. nov., isolated from drinking water.西班牙甲基杆菌新种和水生甲基杆菌新种，从饮用水中分离得到。
Int J Syst Evol Microbiol. 2005 Jan;55(Pt 1):281-287. doi: 10.1099/ijs.0.63319-0.
3
Methylobacterium bacteremia in AIDS.艾滋病患者中的甲基杆菌血症
Clin Microbiol Infect. 1998 Feb;4(2):112-113. doi: 10.1111/j.1469-0691.1998.tb00369.x.
4
Discordant carbapenem susceptibility in Methylobacterium species and its application as a method for phenotypic identification.甲基杆菌属中碳青霉烯药敏结果不一致及其作为表型鉴定方法的应用
J Clin Microbiol. 2001 May;39(5):2037-8. doi: 10.1128/JCM.39.5.2037-2038.2001.
5
Methylobacterium mesophilicum infection: case report and literature review of an unusual opportunistic pathogen.嗜温甲基杆菌感染：一例不寻常机会致病菌的病例报告及文献综述
Clin Infect Dis. 2000 Jun;30(6):936-8. doi: 10.1086/313815.
6
Methylobacterium mesophilica as a cause of persistent bacteremia in a child with lymphoma.嗜中温甲基杆菌作为一名淋巴瘤患儿持续性菌血症的病因
Pediatr Infect Dis J. 1997 Oct;16(10):1007-8. doi: 10.1097/00006454-199710000-00023.
7
Susceptibility testing of clinical isolates of Methylobacterium species.甲基杆菌属临床分离株的药敏试验。
Antimicrob Agents Chemother. 1992 Aug;36(8):1635-8. doi: 10.1128/AAC.36.8.1635.

一名接受造血干细胞移植的急性白血病患者发生罕见的藤泽甲基杆菌感染：首例病例报告

Unusual Methylobacterium fujisawaense Infection in a Patient with Acute Leukaemia Undergoing Hematopoietic Stem Cell Transplantation: First Case Report.

作者信息

Fanci Rosa, Corti Giampaolo, Bartoloni Alessandro, Tortoli Enrico, Mariottini Alessandro, Pecile Patrizia

机构信息

Haematology Unit, Department of Critical Care Medicine and Surgery, Careggi Hospital, University of Florence, School of Medicine, 50134 Florence, Italy.

出版信息

Case Rep Med. 2010;2010:313514. doi: 10.1155/2010/313514. Epub 2010 Apr 8.

DOI:10.1155/2010/313514
PMID:20396386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2852599/
Abstract

Microorganisms of the genus Methylobacterium are facultative methylotrophic, gram-negative rods that are ubiquitous in nature and rarely cause human disease, mostly in subjects with preexisting causes of immune depression. Methylobacterium fujisawaense, first proposed as a new species in 1988, has never been reported as a bacterial agent of human infections so far. Here we describe a case of M. fujisawaense infection in a relapsed acute leukaemia undergoing unrelated allogeneic hematopoietic stem cell transplantation. Molecular identification of an M. fujisawaense strain was obtained from multiple mycobacterial blood cultures.

摘要

甲基杆菌属的微生物是兼性甲基营养型革兰氏阴性杆菌，在自然界中普遍存在，很少引起人类疾病，主要发生在已有免疫抑制病因的患者中。藤泽甲基杆菌于1988年首次被提议作为一个新物种，迄今为止从未有作为人类感染病原体的报道。在此，我们描述了1例正在接受非亲缘异基因造血干细胞移植的复发性急性白血病患者发生藤泽甲基杆菌感染的病例。从多次分枝杆菌血培养中获得了1株藤泽甲基杆菌的分子鉴定结果。