Ito Y
Department of Parasitology, Kitasato University School of Medicine, Sagamihara, Japan.
Int J Parasitol. 1991 Feb;21(1):65-9. doi: 10.1016/0020-7519(91)90121-m.
Congenitally athymic (nude) mice maintained infections of Trichuris muris for at least 40 days post-infection, whereas phenotypically normal mice expelled the worms by 18 days post-infection. Complete worm expulsion occurred in nude mice which had been given spleen cells. On the other hand, a partial resistance to the infection was observed in nude mice which received thymus or mesenteric lymph node cells. No significant worm reduction was seen by injection of immune serum.
先天性无胸腺（裸）小鼠在感染后至少40天内维持着毛首鞭形线虫感染，而表型正常的小鼠在感染后18天就排出了蠕虫。接受脾细胞的裸小鼠出现了完全排虫。另一方面，接受胸腺或肠系膜淋巴结细胞的裸小鼠对感染表现出部分抵抗力。注射免疫血清未见蠕虫数量显著减少。
