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利用重组酵母试验分析污水处理厂废水中的环境内分泌干扰活性。

Analysis of environmental endocrine disrupting activities using recombinant yeast assay in wastewater treatment plant effluents.

机构信息

College of Water Sciences, Beijing Normal University, 100875 Beijing, People's Republic of China.

出版信息

Bull Environ Contam Toxicol. 2010 May;84(5):529-35. doi: 10.1007/s00128-010-0004-2. Epub 2010 Apr 21.

DOI:10.1007/s00128-010-0004-2
PMID:20407748
Abstract

A battery of in vitro recombinant yeast bioassays was conducted to assess the estrogen receptor, androgen receptor, progesterone receptor and thyroid receptor ant/agonistic activities of effluents collected from Datansha wastewater treatment plant (WWTP), furthermore to evaluate the removal efficiencies of endocrine disrupting chemicals in the WWTP. The results showed that estrogenic, anti-androgenic, anti-progesteronic and anti-thyroidic activities were observed in influent. The removal efficiencies of these compounds were more than 80%, which suggested that the present wastewater treatment processes were good enough to remove most of all kinds of endocrine disruption chemicals.

摘要

采用体外重组酵母生物检测方法,评估了大坦沙污水处理厂(WWTP)废水提取物的雌激素受体、雄激素受体、孕激素受体和甲状腺激素受体的抗/激动活性,同时评价了 WWTP 中内分泌干扰物的去除效率。结果表明,进水具有雌激素、抗雄激素、抗孕激素和抗甲状腺活性。这些化合物的去除效率均大于 80%,表明现有污水处理工艺足以去除大部分各种内分泌干扰化学物质。

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