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A secreted enzyme reporter system for MRI.

作者信息

Westmeyer Gil G, Durocher Yves, Jasanoff Alan

机构信息

Department of Biological Engineering, Massachusetts Institute of Technology, 150 Albany Street, NW14-2213, Cambridge, MA 02139, USA.

出版信息

Angew Chem Int Ed Engl. 2010 May 25;49(23):3909-11. doi: 10.1002/anie.200906712.

DOI:10.1002/anie.200906712
PMID:20414908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3065104/
Abstract
摘要

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本文引用的文献

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Magnetic Nanosensors for the Detection of Oligonucleotide Sequences.用于检测寡核苷酸序列的磁性纳米传感器。
Angew Chem Int Ed Engl. 2001 Sep 3;40(17):3204-3206. doi: 10.1002/1521-3773(20010903)40:17<3204::AID-ANIE3204>3.0.CO;2-H.
2
T2 relaxation induced by clusters of superparamagnetic nanoparticles: Monte Carlo simulations.超顺磁性纳米颗粒簇诱导的T2弛豫：蒙特卡罗模拟
Magn Reson Imaging. 2008 Sep;26(7):994-8. doi: 10.1016/j.mri.2008.01.039. Epub 2008 May 13.
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Multi-reservoir device for detecting a soluble cancer biomarker.用于检测可溶性癌症生物标志物的多储库装置。
Lab Chip. 2007 Oct;7(10):1288-93. doi: 10.1039/b705143c. Epub 2007 Jul 20.
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Smart "turn-on" magnetic resonance contrast agents based on aptamer-functionalized superparamagnetic iron oxide nanoparticles.基于适配体功能化超顺磁性氧化铁纳米颗粒的智能“开启”磁共振造影剂。
Chembiochem. 2007 Sep 24;8(14):1675-8. doi: 10.1002/cbic.200700323.
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Genetically controlled MRI contrast mechanisms and their prospects in systems neuroscience research.
Magn Reson Imaging. 2007 Jul;25(6):1004-10. doi: 10.1016/j.mri.2006.11.027. Epub 2007 Apr 23.
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A PARACEST MRI contrast agent to detect enzyme activity.一种用于检测酶活性的PARACEST磁共振成像造影剂。
J Am Chem Soc. 2006 Nov 1;128(43):14032-3. doi: 10.1021/ja063874f.
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Calcium-sensitive MRI contrast agents based on superparamagnetic iron oxide nanoparticles and calmodulin.基于超顺磁性氧化铁纳米颗粒和钙调蛋白的钙敏磁共振成像造影剂。
Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14707-12. doi: 10.1073/pnas.0606749103. Epub 2006 Sep 26.
8
A R2/R1 ratiometric procedure for a concentration-independent, pH-responsive, Gd(III)-based MRI agent.一种用于浓度无关、pH响应性、基于钆（III）的磁共振成像剂的R2/R1比率测量方法。
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A responsive MRI contrast agent to monitor functional cell status.一种用于监测功能性细胞状态的响应性磁共振成像造影剂。
Neuroimage. 2006 Sep;32(3):1142-9. doi: 10.1016/j.neuroimage.2006.05.009. Epub 2006 Jul 11.
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Anal Biochem. 2005 Apr 15;339(2):249-56. doi: 10.1016/j.ab.2005.01.023.