Immpact, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, Scotland.
Bull World Health Organ. 2010 Feb;88(2):147-53. doi: 10.2471/BLT.09.063537. Epub 2009 Oct 14.
The first target of the fifth United Nations Millennium Development Goal is to reduce maternal mortality by 75% between 1990 and 2015. This target is critically off track. Despite difficulties inherent in measuring maternal mortality, interventions aimed at reducing it must be monitored and evaluated to determine the most effective strategies in different contexts. In some contexts, the direct causes of maternal death, such as haemorrhage and sepsis, predominate and can be tackled effectively through providing access to skilled birth attendance and emergency obstetric care. In others, indirect causes of maternal death, such as HIV/AIDS and malaria, make a significant contribution and require alternative interventions. Methods of planning and evaluating maternal health interventions that do not differentiate between direct and indirect maternal deaths may lead to unrealistic expectations of effectiveness or mask progress in tackling specific causes. Furthermore, the need for additional or alternative interventions to tackle the causes of indirect maternal death may not be recognized if all-cause maternal death is used as the sole outcome indicator. This article illustrates the importance of differentiating between direct and indirect maternal deaths by analysing historical data from England and Wales and contemporary data from Ghana, Rwanda and South Africa. The principal aim of the paper is to highlight the need to differentiate deaths in this way when evaluating maternal mortality, particularly when judging progress towards the fifth Millennium Development Goal. It is recommended that the potential effect of maternity services failing to take indirect maternal deaths into account should be modelled.
第五个联合国千年发展目标的第一个目标是在 1990 年至 2015 年期间将产妇死亡率降低 75%。这一目标严重偏离了轨道。尽管衡量产妇死亡率存在固有困难,但必须对旨在降低死亡率的干预措施进行监测和评估,以确定不同情况下最有效的策略。在某些情况下,产妇直接死因,如出血和败血症,占主导地位,可以通过提供熟练的接生和紧急产科护理来有效解决。在其他情况下,产妇间接死因,如艾滋病毒/艾滋病和疟疾,也有重大影响,需要采取替代干预措施。不区分直接和间接产妇死亡的孕产妇保健干预措施规划和评估方法可能导致对有效性的不切实际的期望,或掩盖在解决特定原因方面的进展。此外,如果仅将全因产妇死亡作为唯一的结局指标,可能会忽视针对间接产妇死亡原因的额外或替代干预措施的必要性。本文通过分析英格兰和威尔士的历史数据以及加纳、卢旺达和南非的当代数据,说明了区分直接和间接产妇死亡的重要性。本文的主要目的是强调在评估产妇死亡率,特别是在判断实现第五个千年发展目标的进展时,需要以这种方式区分死亡。建议对产科服务未能考虑间接产妇死亡的潜在影响进行建模。