Centro Superior de Investigaciones en Salud Pública de Valencia (CSISP), Av, Cataluña 21, 46020, Valencia, Spain.
BMC Fam Pract. 2010 May 6;11:33. doi: 10.1186/1471-2296-11-33.
There is little available data regarding the epidemiology of herpes zoster (HZ) in Spain. This study's main goal was to estimate the annual incidence of HZ in the Autonomous Community of Valencia.
From December 1st 2006 to December 1st 2007, a prospective study was carried out in 24 primary health care centres that together provide care for a population of 36,030 persons aged >14 years. We included all adult patients with a clinical diagnosis of HZ who were seen at these centres during the one-year study period. Demographic (i.e., age, gender, and area of residence) and clinical data were also collected from these patients.
A total of 146 cases of HZ were identified during the study period. The annual incidence of HZ was 4.1/1,000 individuals >14 years of age (95% confidence interval [CI]: 3.4-4.7). Cases of HZ were predominantly unilateral and most commonly affected women and people living in rural areas. The most frequently reported symptoms were pain, dysesthesia and itching. A total of 46% of patients also had underlying illnesses (e.g., chronic diseases and/or malignancy) and 24% of patients experienced complications, which were mostly ocular in nature. A total of 91% of patients were treated with antiviral drugs. The median time from symptoms onset to diagnosis was 6.3 days (range: 2.0-8.3).
HZ is a common illness in our region (especially in the older population) that causes a significant clinical burden on primary care providers.
西班牙带状疱疹（HZ）的流行病学数据很少。本研究的主要目的是估计巴伦西亚自治区的 HZ 年发病率。
2006 年 12 月 1 日至 2007 年 12 月 1 日，对 24 个初级保健中心进行了前瞻性研究，这些中心共同为 36030 名> 14 岁的人群提供服务。我们纳入了在这一年的研究期间在这些中心就诊的患有 HZ 临床诊断的所有成年患者。还从这些患者中收集了人口统计学（即年龄、性别和居住地区）和临床数据。
在研究期间共发现 146 例 HZ。HZ 的年发病率为 14 岁以上人群 4.1/1000 人（95%置信区间 [CI]：3.4-4.7）。HZ 病例主要为单侧，最常见的是女性和居住在农村地区的人。最常见的症状是疼痛、感觉异常和瘙痒。共有 46%的患者有基础疾病（如慢性病和/或恶性肿瘤），24%的患者出现并发症，主要是眼部并发症。共有 91%的患者接受了抗病毒药物治疗。从症状出现到诊断的中位时间为 6.3 天（范围：2.0-8.3）。
HZ 在我们地区是一种常见疾病（尤其是在老年人群中），对初级保健提供者造成了重大的临床负担。
