Teixeira Luciana de Almeida Silva, Lopes Juliana Salviano Mendonça, Martins André Guilherme da Costa, Campos Fernando Augusto Batista, Miranzi Sybelle de Souza Castro, Nascentes Gabriel Antônio Nogueira
Universidade Federal do Triângulo Mineiro, Uberaba, Brasil.
Cad Saude Publica. 2010 Mar;26(3):624-30. doi: 10.1590/s0102-311x2010000300019.
The clinical picture of dengue is characterized by a maximum duration of 14 days despite frequent complaints of longer symptoms. This study evaluated the occurrence of persistent symptoms (> 14 days) and its impact on daily life. A hundred eighteen patients were interviewed, and the main symptoms at diagnosis were mialgia (98.3%), fever (97.5%) and weakness (95.8%). The presence of at least a persistent symptom was related by 77 (65.2%) individuals of wich 10 (8.5%) described it as intense and lasting for 30 days or more. The most persistent symptoms mentioned were weakness (58 cases), hiporexia (49) and sleepiness (40), occurring mostly in women, with odds ratio: 5.4 (IC95%: 2.3-12.3). A significant association between the persistence of the symptoms and the history of extra expenses (p = 0,02) was found, as well as a delay to return to normal activities (p < 0.001). Thus, it was verified that dengue presented a relevant impact on every day life, even after 14 days, a fact wich was associated with the presence of persistent symptoms of the illness.
登革热的临床症状表现为最长持续14天,尽管患者经常抱怨症状持续时间更长。本研究评估了持续症状(>14天)的发生情况及其对日常生活的影响。对118名患者进行了访谈,诊断时的主要症状为肌痛(98.3%)、发热(97.5%)和虚弱(95.8%)。77名(65.2%)个体存在至少一种持续症状,其中10名(8.5%)将其描述为严重且持续30天或更长时间。提及最多的持续症状为虚弱(58例)、食欲减退(49例)和嗜睡(40例),大多发生在女性中,优势比为5.4(95%置信区间:2.3 - 12.3)。发现症状持续与额外费用史之间存在显著关联(p = 0.02),以及恢复正常活动延迟(p < 0.001)。因此,证实了登革热即使在14天后仍对日常生活有显著影响,这一事实与疾病持续症状的存在有关。