利用固定化海洋微藻帕夫洛娃藻对双酚A和二苯甲酮进行糖基化生物修复

Bioremediation of Bisphenol A and Benzophenone by Glycosylation with Immobilized Marine Microalga Pavlova sp.

作者信息

Shimoda Kei, Hamada Hiroki

机构信息

Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.

出版信息

Environ Health Insights. 2009 Sep 23;3:89-94. doi: 10.4137/ehi.s2758.

DOI:10.4137/ehi.s2758

PMID:20508758

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2872572/

Abstract

Cultured cells of Pavlova sp. glycosylated bisphenol A to its mono-glucoside, 2-(4-beta-D-glucopyranosyloxyphenyl)-2-hydroxyphenylpropane (9%). Use of immobilized Pavlova cells in sodium alginate gel improved yield of the product (17%). On the other hand, Pavlova cell cultures converted benzophenone into diphenylmethanol (49%) and diphenylmethyl beta-D-glucopyranoside (6%). Incubation of benzophenone with immobilized Pavlova cells gave products in higher yields; the yields of diphenylmethanol and diphenylmethyl beta-D-glucopyranoside were 85 and 15%, respectively.

摘要

巴氏藻属的培养细胞将双酚A糖基化为其单葡糖苷，即2-(4-β-D-吡喃葡萄糖氧基苯基)-2-羟基苯丙烷（9%）。在海藻酸钠凝胶中使用固定化巴氏藻细胞提高了产物的产量（17%）。另一方面，巴氏藻细胞培养物将二苯甲酮转化为二苯甲醇（49%）和二苯甲基β-D-吡喃葡萄糖苷（6%）。用固定化巴氏藻细胞孵育二苯甲酮可得到更高产量的产物；二苯甲醇和二苯甲基β-D-吡喃葡萄糖苷的产量分别为85%和15%。