Cheng Shi-Yie, Lin En-Hung, Wen Zhi-Hong, Chiang Michael Yen-Nan, Duh Chang-Yih
Department of Marine Biotechnology and Resources, National Sun Yat-sen University.
Chem Pharm Bull (Tokyo). 2010 Jun;58(6):848-51. doi: 10.1248/cpb.58.848.
Chemical investigations of the Formosan soft coral Cespitularia hypotentaculata ROXAS led to the isolation of two new verticillane diterpenoids, cespitularins R and S (1, 2), along with seven known compounds (3-9). The structures of these isolated compounds were elucidated on the basis of extensive spectroscopic analysis and by comparison with those of reported in literature. The anti-inflammatory activity using RAW 264.7 macrophages of compounds 1-9 were evaluated in vitro.
对台湾软珊瑚罗氏丛柳珊瑚（Cespitularia hypotentaculata ROXAS）进行化学研究，从中分离出两种新的轮状二萜类化合物，丛柳珊瑚素R和S（1, 2），以及七种已知化合物（3 - 9）。通过广泛的光谱分析并与文献报道的结构进行比较，阐明了这些分离化合物的结构。在体外评估了化合物 1 - 9 对RAW 264.7巨噬细胞的抗炎活性。
