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本文引用的文献

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Caffeic acid protects rat heart mitochondria against isoproterenol-induced oxidative damage.咖啡酸可保护大鼠心脏线粒体免受异丙肾上腺素诱导的氧化损伤。
Cell Stress Chaperones. 2010 Nov;15(6):791-806. doi: 10.1007/s12192-010-0187-9. Epub 2010 Apr 9.
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SIRT1 takes a backseat to AMPK in the regulation of insulin sensitivity by resveratrol.在白藜芦醇对胰岛素敏感性的调节中,SIRT1的作用次于AMPK。
Diabetes. 2010 Mar;59(3):551-3. doi: 10.2337/db09-1732.
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Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1.二甲双胍通过 AMPK、LKB1 和 SKN-1 诱导类似饮食限制的状态和氧化应激反应,从而延长秀丽隐杆线虫的健康寿命。
PLoS One. 2010 Jan 18;5(1):e8758. doi: 10.1371/journal.pone.0008758.
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Diet effects on honeybee immunocompetence.饮食对蜜蜂免疫能力的影响。
Biol Lett. 2010 Aug 23;6(4):562-5. doi: 10.1098/rsbl.2009.0986. Epub 2010 Jan 20.
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The genetic map of Artemisia annua L. identifies loci affecting yield of the antimalarial drug artemisinin.黄花蒿的遗传图谱确定了影响抗疟药物青蒿素产量的基因座。
Science. 2010 Jan 15;327(5963):328-31. doi: 10.1126/science.1182612.
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Systemic induction of monoterpene biosynthesis in Origanumxmajoricum by soil bacteria.土壤细菌对马郁兰中单萜生物合成的系统诱导。
J Agric Food Chem. 2010 Jan 13;58(1):650-4. doi: 10.1021/jf9030629.
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Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells.高压氧诱导人微血管内皮细胞产生细胞保护和血管生成反应。
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8
Design and development of nanovehicle-based delivery systems for preventive or therapeutic supplementation with flavonoids.基于纳米载体的设计与开发,用于预防或治疗黄酮类化合物的补充。
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Plant Physiol. 2009 Dec;151(4):1902-17. doi: 10.1104/pp.109.143735. Epub 2009 Oct 7.
10
Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts.植物多酚植物药复合物的生物利用度和活性:水飞蓟素、姜黄素、绿茶和葡萄籽提取物
Altern Med Rev. 2009 Sep;14(3):226-46.

异种生物效应:从植物应激反应进化的漫长历史中获得健康益处。

Xenohormesis: health benefits from an eon of plant stress response evolution.

机构信息

Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Denver, School of Medicine, Aurora, CO, USA.

出版信息

Cell Stress Chaperones. 2010 Nov;15(6):761-70. doi: 10.1007/s12192-010-0206-x. Epub 2010 Jun 4.

DOI:10.1007/s12192-010-0206-x
PMID:20524162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3024065/
Abstract

Xenohormesis is a biological principle that explains how environmentally stressed plants produce bioactive compounds that can confer stress resistance and survival benefits to animals that consume them. Animals can piggyback off products of plants' sophisticated stress response which has evolved as a result of their stationary lifestyle. Factors eliciting the plant stress response can judiciously be employed to maximize yield of health-promoting plant compounds. The xenohormetic plant compounds can, when ingested, improve longevity and fitness by activating the animal's cellular stress response and can be applied in drug discovery, drug production, and nutritional enhancement of diet.

摘要

异种外激素作用是一个生物学原理,它解释了环境压力下的植物如何产生生物活性化合物,这些化合物可以赋予食用它们的动物抗逆性和生存优势。动物可以利用植物复杂应激反应的产物,这些产物是由于它们的固定生活方式而进化而来的。诱发植物应激反应的因素可以被明智地利用,以最大限度地提高促进健康的植物化合物的产量。当异种外激素植物化合物被摄入时,可以通过激活动物的细胞应激反应来延长寿命和提高适应性,可应用于药物发现、药物生产和饮食营养增强。