University of California at Los Angeles School of Dentistry, University of California, Los Angeles, CA 90095-1668, USA.
BMC Bioinformatics. 2010 Jun 3;11:302. doi: 10.1186/1471-2105-11-302.
The Salivaomics Knowledge Base (SKB) is designed to serve as a computational infrastructure that can permit global exploration and utilization of data and information relevant to salivaomics. SKB is created by aligning (1) the saliva biomarker discovery and validation resources at UCLA with (2) the ontology resources developed by the OBO (Open Biomedical Ontologies) Foundry, including a new Saliva Ontology (SALO).
We define the Saliva Ontology (SALO; http://www.skb.ucla.edu/SALO/) as a consensus-based controlled vocabulary of terms and relations dedicated to the salivaomics domain and to saliva-related diagnostics following the principles of the OBO (Open Biomedical Ontologies) Foundry.
The Saliva Ontology is an ongoing exploratory initiative. The ontology will be used to facilitate salivaomics data retrieval and integration across multiple fields of research together with data analysis and data mining. The ontology will be tested through its ability to serve the annotation ('tagging') of a representative corpus of salivaomics research literature that is to be incorporated into the SKB.
唾液组学知识库（SKB）旨在作为一种计算基础设施，能够允许对与唾液组学相关的数据和信息进行全球探索和利用。SKB 通过将（1）UCLA 的唾液生物标志物发现和验证资源与（2）OBO（开放生物医学本体论）基金会开发的本体论资源对齐来创建，包括一个新的唾液本体论（SALO）。
我们将唾液本体论（SALO；http://www.skb.ucla.edu/SALO/）定义为一个基于共识的术语和关系的受控词汇表，专门用于唾液组学领域以及唾液相关诊断，遵循 OBO（开放生物医学本体论）基金会的原则。
唾液本体论是一个正在进行的探索性计划。该本体论将用于促进跨多个研究领域的唾液组学数据检索和集成，以及数据分析和数据挖掘。该本体论将通过其为代表性的唾液组学研究文献语料库的注释（“标记”）服务的能力进行测试，该语料库将被纳入 SKB。
