金纳米颗粒平台作为药物和生物大分子的输送系统。
Gold nanoparticle platforms as drug and biomacromolecule delivery systems.
机构信息
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
出版信息
J Control Release. 2010 Nov 20;148(1):122-127. doi: 10.1016/j.jconrel.2010.06.004. Epub 2010 Jun 11.
Abstract
Gold nanoparticles (AuNPs) are a suitable platform for development of efficient delivery systems. AuNPs can be easily synthesized, functionalized, and are biocompatible. The tunability of the AuNP monolayer allows for complete control of surface properties for targeting and stability/release using these nanocarriers. This review will discuss several delivery strategies utilizing AuNPs.
摘要
金纳米粒子（AuNPs）是开发高效递药系统的合适平台。AuNPs 易于合成、功能化且生物相容性好。AuNP 单层的可调变性允许使用这些纳米载体完全控制表面性质，以实现靶向和稳定性/释放。本文将讨论几种利用 AuNPs 的递药策略。
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