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影响传统腰椎开放椎间盘切除术临床结局的预后因素分析:临床及影像学预后因素

An analysis of the prognostic factors affecing the clinical outcomes of conventional lumbar open discectomy : clinical and radiological prognostic factors.

作者信息

Lee Jae Chul, Kim Min-Soo, Shin Byung-Joon

机构信息

Department of Orthopaedic Surgery & Spine Center, Soonchunhyang University College of Medicine, Seoul, Korea.

出版信息

Asian Spine J. 2010 Jun;4(1):23-31. doi: 10.4184/asj.2010.4.1.23. Epub 2010 Apr 30.

Abstract

STUDY DESIGN

This is a retrospective study.

PURPOSE

We wanted to examine the clinical and radiological prognostic factors affecting the postoperative clinical outcome of patients with lumbar disc herniation and who underwent open discectomy.

OVERVIEW OF LITERATURE

Conventional open discectomy has been widely used as a treatment regimen for the management of lumbar disc herniation. Still, much controversy exists regarding the factors that affect the postoperative clinical outcomes.

METHODS

The current study was conducted on 40 patients who were diagnosed with lumbar disc herniation by the senior surgeon of our department from March 2004 to June 2007. These patients were refractory to conservative treatment and they could be followed up for more than one year following their surgical treatments. Preoperatively, after postoperative year 1 and at the final follow-up, a comparison was made for the Oswestry disability index (ODI) scores and the visual analogue scale (VAS) scores that indicated low back pain and radiating pain. For identifying prognostic factors, an analysis was also performed for such factors as age, gender, the operated level, the duration of preoperative low back pain and radiating pain, a smoking history, the body mass index and whether the surgery was revision or the primary operation. A radiological analysis, based on the preoperative plain flexion-extension radiography, was performed for the presence of mild segmental instability of < 3 mm, spondylolysis and disc space narrowing. Pfirrmann's degenerative grade of the disc, the degree of herniation and whether a herniation was central or massive on the magnetic resonance imaging scans.

RESULTS

At the final follow-up, the ODI was significantly higher in the cases of revision as compared with the cases of primary operation. The female gender also had a tendency for a poor ODI as compared with that of the men, but this had only borderline statistical significance. There was significant correlation between the preoperative ODI and the preoperative VAS indicating radiating pain. At a final follow up, the low back pain VAS score was significantly lower in the extruded cases as compared with that of the protruded or sequestrated cases.

CONCLUSIONS

Following an analysis for detecting the prognostic factors of open discectomy, the final clinical outcome was found to be poor for the revision surgery cases. In regard to the type of herniation, the degree of low back pain was relatively lower at a final follow-up for the extruded cases as compared with that for the protruded or sequestrated cases. Open discectomy surgery should be performed after evaluating the patients' various prognostic factors that could affect the final clinical outcome.

摘要

研究设计

这是一项回顾性研究。

目的

我们旨在研究影响腰椎间盘突出症患者行开放性椎间盘切除术术后临床结局的临床及影像学预后因素。

文献综述

传统开放性椎间盘切除术已被广泛用作治疗腰椎间盘突出症的一种治疗方案。然而,关于影响术后临床结局的因素仍存在诸多争议。

方法

本研究纳入了2004年3月至2007年6月期间由我院资深外科医生诊断为腰椎间盘突出症的40例患者。这些患者对保守治疗无效,且术后随访时间超过一年。术前、术后1年及末次随访时,比较Oswestry功能障碍指数(ODI)评分以及表示腰痛和放射痛的视觉模拟量表(VAS)评分。为确定预后因素,还对年龄、性别、手术节段、术前腰痛和放射痛持续时间、吸烟史、体重指数以及手术是翻修手术还是初次手术等因素进行了分析。基于术前屈伸位X线片进行影像学分析,以确定是否存在<3mm的轻度节段性不稳定、椎弓根峡部裂和椎间隙狭窄。根据磁共振成像扫描结果分析椎间盘的Pfirrmann退变分级、突出程度以及突出是中央型还是巨大型。

结果

末次随访时,翻修手术患者的ODI显著高于初次手术患者。与男性相比,女性的ODI也有较差的趋势,但仅具有边缘统计学意义。术前ODI与术前表示放射痛的VAS之间存在显著相关性。末次随访时,脱出型病例的腰痛VAS评分显著低于突出型或游离型病例。

结论

在分析开放性椎间盘切除术的预后因素后发现,翻修手术病例的最终临床结局较差。就突出类型而言,末次随访时脱出型病例的腰痛程度相对低于突出型或游离型病例。在评估可能影响最终临床结局的各种预后因素后,再行开放性椎间盘切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4326/2900165/c8970054e5e5/asj-4-23-g001.jpg

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