Lelli Diana, Cortese Livio, Pedone Claudio
Area di Geriatria, Università Campus Bio-Medico di Roma, Roma, Italy.
Adv Exp Med Biol. 2021;1308:217-224. doi: 10.1007/978-3-030-64872-5_15.
Sleep disorders have a high prevalence both in the general population and especially in specific populations such older adults and oncologic patients. Impacting on quality of life, they often translate in drug prescription, with consequent increased risk of drug-drug interactions and adverse drug reactions. In the last years several products derived from plants have been developed with the aim of treating insomnia with lower risk of side effects. Despite several studies have been performed with this aim, the available evidence is inconclusive, and reviews summarizing the most recent evidences on the effectiveness of plant-derived products in treating insomnia are lacking.This narrative review aims at summarizing the evidences of the mechanism of action, effectiveness and safety of the most commonly used plant-derived products for the treatment of sleep disorders (Valerian, Lemon balm, Passionflower, Chamomile, Hops, and Jujube).
睡眠障碍在普通人群中普遍存在，在特定人群如老年人和肿瘤患者中更为常见。它们会影响生活质量，常常导致药物处方，进而增加药物相互作用和药物不良反应的风险。近年来，已经开发了几种植物衍生产品，旨在以较低的副作用风险治疗失眠。尽管已经为此进行了多项研究，但现有证据尚无定论，且缺乏总结植物衍生产品治疗失眠有效性的最新证据的综述。本叙述性综述旨在总结最常用的植物衍生产品治疗睡眠障碍（缬草、柠檬香蜂草、西番莲、洋甘菊、啤酒花和枣）的作用机制、有效性和安全性的证据。
