Department of Neurology, Chinese PLA General Hospital, Fuxing Road 28, Haidian District, 100853 Beijing, China,
J Headache Pain. 2012 Oct;13(7):531-6. doi: 10.1007/s10194-012-0470-5. Epub 2012 Jul 19.
The objective of this study is to evaluate the association between body mass index (BMI) and migraine in general population Chinese cohort. This was a cross-sectional secondary analysis from a general population Chinese cohort of men and women of reproductive and post-reproductive age ranging between 18 and 65 years. Migraine was defined utilizing ICHD criteria. Body mass indices were calculated using measured height and weight and categorized based on the World Health Organizations criteria. The 1-year period prevalence of migraine was 9.3 %. No association was identified between migraine and those with a BMI < 30.0. Compared to those with normal BMI (18.5-23.0), those with BMI ≥ 30 (morbid obesity) had a greater prevalence of migraine (8.6 vs. 13.8 %, p = 0.000). Multivariate-adjusted odds ratio demonstrated that those with morbid obesity had a greater than twofold increased odds of migraine [OR 2.10 (1.39-3.12)] as compared to those with a BMI between 18.5 and 23.0. No association was found between obesity and migraine severity, frequency, or disability. Morbid obesity was associated with twofold increased odds of migraine in this Chinese men and women cohort of predominantly reproductive age.
本研究旨在评估中国一般人群中体重指数(BMI)与偏头痛之间的关联。这是一项针对生育和生育后年龄段在 18 至 65 岁之间的中国男女一般人群的横断面二次分析。偏头痛利用 ICHD 标准进行定义。体重指数通过测量的身高和体重计算得出,并根据世界卫生组织的标准进行分类。偏头痛的 1 年期间患病率为 9.3%。偏头痛与 BMI<30.0 的人群之间没有关联。与正常 BMI(18.5-23.0)的人群相比,BMI≥30(病态肥胖)的人群偏头痛患病率更高(8.6%比 13.8%,p=0.000)。多变量调整后的优势比表明,与 BMI 在 18.5 至 23.0 之间的人群相比,病态肥胖人群偏头痛的发生几率增加了两倍以上[比值比 2.10(1.39-3.12)]。肥胖与偏头痛的严重程度、频率或残疾之间没有关联。在以生育年龄为主的中国男女人群队列中,病态肥胖与偏头痛的发生几率增加两倍有关。