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体重指数及其与偏头痛各种特征的关联:来自沙特阿拉伯的横断面研究。

Body mass index and its association with various features of migraine: A cross-sectional study from Saudi Arabia.

机构信息

Department of Neurology, College of Medicine, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.

Department of Pediatric Neurology, College of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

出版信息

Ann Afr Med. 2021 Oct-Dec;20(4):288-292. doi: 10.4103/aam.aam_63_20.

DOI:10.4103/aam.aam_63_20
PMID:34893567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8693735/
Abstract

INTRODUCTION

Migraine is a highly prevalent condition, and prevalence of obesity is also increasing. Results of studies addressing association of body mass index (BMI) with migraine and its features are conflicting. In this cross-sectional study, we aim to assess association between BMI and various migraine features.

METHODS

This study was conducted in the Headache Clinic of King Fahd Hospital of University, Al Khobar, Saudi Arabia. Interviews were conducted by three consultant neurologists. Migraine was defined according to the International Headache Society and BMI was calculated as weight (kilograms)/height (m).

RESULTS

Of total of 121 patients, 79% were female. Almost 87.6% of patients were taking prophylactic medications. Majority of patients had attack for more than 24 h (60.3%), pulsating character (81%), moderate-to-severe intensity (92.6%), associated with nausea and/or vomiting (75.2%), and photophobia/phonophobia (91.7%). About 29.8% of patients were normal weight, 28.1% were overweight, and 39.7% were obese and morbidly obese. There was insignificant association between various categories of BMI and features of migraine, that is, unilateral location (P = 0.385), pulsating character (P = 0.571), moderate-to-severe intensity (P = 0.187), nausea and/or vomiting (P = 0.582), and photophobia and/or phonophobia (P = 0.444).

CONCLUSION

In our study, we did not find an association between BMI and various features of migraine.

摘要

简介

偏头痛是一种高发疾病,肥胖的发病率也在上升。研究偏头痛与体重指数(BMI)之间的关联及其特征的结果存在矛盾。在这项横断面研究中,我们旨在评估 BMI 与各种偏头痛特征之间的关系。

方法

这项研究在沙特阿拉伯阿尔科巴的法赫德国王大学医院头痛诊所进行。访谈由三位顾问神经病学家进行。偏头痛根据国际头痛协会的标准进行定义,BMI 计算为体重(千克)/身高(米)。

结果

在总共 121 名患者中,79%为女性。几乎 87.6%的患者正在服用预防药物。大多数患者的发作时间超过 24 小时(60.3%),具有搏动性特征(81%),中度至重度强度(92.6%),伴有恶心和/或呕吐(75.2%),畏光和/或畏声(91.7%)。约 29.8%的患者体重正常,28.1%超重,39.7%肥胖,39.7%为病态肥胖。各种 BMI 类别与偏头痛的特征之间没有显著关联,即单侧位置(P = 0.385)、搏动性特征(P = 0.571)、中度至重度强度(P = 0.187)、恶心和/或呕吐(P = 0.582),以及畏光和/或畏声(P = 0.444)。

结论

在我们的研究中,我们没有发现 BMI 与偏头痛的各种特征之间存在关联。

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Behav Neurol. 2018 Apr 19;2018:6585734. doi: 10.1155/2018/6585734. eCollection 2018.
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Tyrosine Phosphorylation of NR2B Contributes to Chronic Migraines via Increased Expression of CGRP in Rats.NR2B的酪氨酸磷酸化通过增加大鼠降钙素基因相关肽(CGRP)的表达导致慢性偏头痛。
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