Costa Adilson, Lage Denise, Moisés Thaís Abdalla
Pontifícia Universidade Católica de Campinas, Campinas, SP, Brasil.
An Bras Dermatol. 2010 May-Jun;85(3):346-53. doi: 10.1590/s0365-05962010000300008.
Numerous studies were published over the last 50 years to investigate whether diet is associated with the etiology of acne. Although older studies well known by dermatologists that refute the association between acne and diet exist, their scientific foundation is weak. New articles have recently brought to light evidence contrary to previous findings. Therefore, we would like to investigate whether diet, directly or indirectly, influences one or more of the four fundamental etiopathogenic pillars of acne: (1) hyperproliferation of basal keratinocytes, (2) increase of sebaceous production, (3) colonization by Propionibacterium acnes, and (4) inflammation.
在过去50年里发表了大量研究,以探究饮食是否与痤疮的病因有关。尽管皮肤科医生熟知的一些较早期研究驳斥了痤疮与饮食之间的关联,但其科学依据薄弱。最近的新文章揭示了与先前研究结果相反的证据。因此,我们想要研究饮食是否直接或间接地影响痤疮四个基本致病因素中的一个或多个,这四个因素分别是:(1)基底角质形成细胞的过度增殖,(2)皮脂分泌增加,(3)痤疮丙酸杆菌的定植,以及(4)炎症。