小鼠发育的超声和磁共振显微成像
Ultrasound and magnetic resonance microimaging of mouse development.
作者信息
Nieman Brian J, Turnbull Daniel H
机构信息
Mouse Imaging Centre, Hospital for Sick Children, Department of Medical Biophysics, University of Toronto, Toronto, Canada.
出版信息
Methods Enzymol. 2010;476:379-400. doi: 10.1016/S0076-6879(10)76021-3.
Abstract
Ultrasound biomicroscopy (UBM) and magnetic resonance microimaging (micro-MRI) provide noninvasive, high-resolution images in mouse embryos and neonates, enabling volumetric and functional analyses of phenotypes, including longitudinal imaging of individual mice over critical stages of in utero and early-postnatal development. In this chapter, we describe the underlying principles of UBM and micro-MRI, including the advantages and limitations of these approaches for studies of mouse development, and providing a number of examples to illustrate their use. To date, most imaging studies have focused on the developing nervous and cardiovascular systems, which are also reflected in the examples shown in this chapter, but we also discuss the future application of these methods to other organ systems.
摘要
超声生物显微镜（UBM）和磁共振显微成像（显微MRI）可在小鼠胚胎和新生小鼠中提供无创的高分辨率图像，从而能够对表型进行体积分析和功能分析，包括在子宫内和出生后早期发育的关键阶段对单个小鼠进行纵向成像。在本章中，我们描述了UBM和显微MRI的基本原理，包括这些方法在小鼠发育研究中的优缺点，并提供了一些实例来说明它们的应用。迄今为止，大多数成像研究都集中在发育中的神经和心血管系统，本章所示的实例也反映了这一点，但我们也讨论了这些方法在其他器官系统中的未来应用。
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本文引用的文献
1
Three-dimensional micro-MRI analysis of cerebral artery development in mouse embryos.
Magn Reson Med. 2009 Dec;62(6):1431-9. doi: 10.1002/mrm.22113.
2
A new 15-50 MHz array-based micro-ultrasound scanner for preclinical imaging.
Ultrasound Med Biol. 2009 Oct;35(10):1700-8. doi: 10.1016/j.ultrasmedbio.2009.04.012. Epub 2009 Aug 3.
3
Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue.
Magn Reson Med. 2009 Jul;62(1):26-34. doi: 10.1002/mrm.21977.
4
Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8.
Alcohol Clin Exp Res. 2009 Jun;33(6):1001-11. doi: 10.1111/j.1530-0277.2009.00921.x. Epub 2009 Mar 19.
5
Three-dimensional, in vivo MRI with self-gating and image coregistration in the mouse.
Magn Reson Med. 2009 May;61(5):1148-57. doi: 10.1002/mrm.21945.
6
MicroCT for developmental biology: a versatile tool for high-contrast 3D imaging at histological resolutions.
Dev Dyn. 2009 Mar;238(3):632-40. doi: 10.1002/dvdy.21857.
7
Diffusion tensor imaging of ex vivo cervical spinal cord specimens: the immediate and long-term effects of fixation on diffusivity.
Anat Rec (Hoboken). 2009 Feb;292(2):234-41. doi: 10.1002/ar.20823.
8
Fixation, not death, reduces sensitivity of DTI in detecting optic nerve damage.
Neuroimage. 2009 Feb 1;44(3):611-9. doi: 10.1016/j.neuroimage.2008.10.032. Epub 2008 Nov 5.
9
High-resolution magnetic resonance histology of the embryonic and neonatal mouse: a 4D atlas and morphologic database.
Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12331-6. doi: 10.1073/pnas.0805747105. Epub 2008 Aug 19.
10
Three-dimensional analysis of vascular development in the mouse embryo.
PLoS One. 2008 Aug 6;3(8):e2853. doi: 10.1371/journal.pone.0002853.
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