Tortoli Enrico, Böttger Erik C, Fabio Anna, Falsen Enevold, Gitti Zoe, Grottola Antonella, Klenk Hans-Peter, Mannino Roberta, Mariottini Alessandro, Messinò Massimino, Pecorari Monica, Rumpianesi Fabio
Regional Reference Center for Mycobacteria, Microbiology and Virology Laboratory, Careggi University Hospital, Florence, Italy.
Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
Int J Syst Evol Microbiol. 2011 Jul;61(Pt 7):1606-1611. doi: 10.1099/ijs.0.025601-0. Epub 2010 Aug 6.
Four strains isolated in the last 15 years were revealed to be identical in their 16S rRNA gene sequences to MCRO19, the sequence of which was deposited in GenBank in 1995. In a polyphasic analysis including phenotypic and genotypic features, the five strains (including MCRO19), which had been isolated in four European countries, turned out to represent a unique taxonomic entity. They are scotochromogenic slow growers and are genetically related to the group that included Mycobacterium simiae and 15 other species. The novel species Mycobacterium europaeum sp. nov. is proposed to accommodate these five strains. Strain FI-95228(T) ( = DSM 45397(T) = CCUG 58464(T)) was chosen as the type strain. In addition, a thorough revision of the phenotypic and genotypic characters of the species related to M. simiae was conducted which leads us to suggest the denomination of the 'Mycobacterium simiae complex' for this group.
结果显示,在过去15年中分离出的4株菌株,其16S rRNA基因序列与MCRO19完全相同,MCRO19的序列于1995年保存在GenBank中。在一项包括表型和基因型特征的多相分析中,这5株菌株(包括MCRO19)分别从4个欧洲国家分离得到,结果表明它们代表了一个独特的分类实体。它们是暗产色的缓慢生长菌,在基因上与包括猿分枝杆菌和其他15个物种的类群相关。提议将新物种欧洲分枝杆菌(Mycobacterium europaeum sp. nov.)用于容纳这5株菌株。选择菌株FI-95228(T)(=DSM 45397(T)=CCUG 58464(T))作为模式菌株。此外,对与猿分枝杆菌相关物种的表型和基因型特征进行了全面修订,这使我们建议将该类群命名为“猿分枝杆菌复合群”。