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在生态系统层面驱动长寿的异种应激、应激和细胞抑制选择力。

Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level.

作者信息

Goldberg Alexander A, Kyryakov Pavlo, Bourque Simon D, Titorenko Vladimir I

机构信息

Department of Biology, Concordia University, Montreal, Quebec H4B 1R6, Canada.

出版信息

Aging (Albany NY). 2010 Aug;2(8):461-70. doi: 10.18632/aging.100186.

DOI:10.18632/aging.100186
PMID:20693605
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2954037/
Abstract

We recently found that lithocholic acid (LCA), a bile acid, extends yeast longevity. Unlike mammals, yeast do not synthesize bile acids. We therefore propose that bile acids released into the environment by mammals may act as interspecies chemical signals providing longevity benefits to yeast and, perhaps, other species within an ecosystem.

摘要

我们最近发现，胆汁酸石胆酸（LCA）可延长酵母的寿命。与哺乳动物不同，酵母不会合成胆汁酸。因此，我们提出，哺乳动物释放到环境中的胆汁酸可能作为种间化学信号，为酵母以及生态系统中的其他物种带来延长寿命的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222c/2954037/e1be202d8361/aging-02-461-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222c/2954037/f26e10942e1a/aging-02-461-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222c/2954037/f7fbf8aa05f1/aging-02-461-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222c/2954037/e1be202d8361/aging-02-461-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222c/2954037/f26e10942e1a/aging-02-461-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222c/2954037/f7fbf8aa05f1/aging-02-461-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222c/2954037/e1be202d8361/aging-02-461-g003.jpg

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