UCLA School of Medicine, Los Angeles, CA 90024,
J Clin Exp Neuropsychol. 2011 Feb;33(2):200-9. doi: 10.1080/13803395.2010.499357. Epub 2010 Aug 6.
This study examined the effects of aging and cognitive impairment on medication and finance management in an HIV sample. We observed main effects of age (older < younger) and neuropsychological impairment on functional task performance. Interactions between age and cognition demonstrated that older impaired individuals performed significantly more poorly than all other comparison groups. There were no relationships between laboratory performance and self-reported medication and finance management. The interaction of advancing age and cognitive impairment may confer significant functional limitations for HIV individuals that may be better detected by performance-based measures of functional abilities rather than patient self-report.
本研究考察了衰老和认知障碍对 HIV 样本中药物和财务管理的影响。我们观察到年龄(老年人<年轻人)和神经心理学障碍对功能任务表现的主要影响。年龄与认知之间的相互作用表明,年龄较大且认知受损的个体表现明显差于所有其他比较组。实验室表现与自我报告的药物和财务管理之间没有关系。年龄的增长和认知障碍的相互作用可能会给 HIV 个体带来显著的功能限制,而通过基于表现的功能能力测量可能比患者自我报告更好地检测到这些限制。