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壳聚糖-聚丙烯酸磁性微球的制备及性能研究。

Preparation and characterization of chitosan poly(acrylic acid) magnetic microspheres.

机构信息

Department of radiology, The First Affiliated Hospital of Soochow University, and College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215007, China.

出版信息

Mar Drugs. 2010 Jul 23;8(7):2212-22. doi: 10.3390/md8072212.

DOI:10.3390/md8072212
PMID:20714433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2920552/
Abstract

Spherical microparticles, capable of responding to magnetic fields, were prepared by encapsulating dextran-coated Fe3O4 nanoparticles into chitosan poly(acrylic acid) (PAA) microspheres template. The obtained magnetic microspheres were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-ray powder diffraction (XRD), and thermogravimetry (TG). The results showed that the microspheres were formed and demonstrated magnetic behavior in an applied magnetic field. In addition, magnetite particles were well encapsulated and the composite particles have high magnetite content, which was more than 40%.

摘要

通过将葡聚糖包覆的 Fe3O4 纳米粒子包封到壳聚糖聚(丙烯酸) (PAA) 微球模板中,制备了能够响应磁场的球形微球。通过透射电子显微镜 (TEM)、傅里叶变换红外光谱 (FT-IR)、扫描电子显微镜 (SEM)、X 射线粉末衍射 (XRD) 和热重分析 (TG) 对得到的磁性微球进行了表征。结果表明,微球形成并在施加磁场时表现出磁性。此外,磁性粒子被很好地包封,并且复合粒子具有高的磁性粒子含量,超过 40%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/165a87606306/marinedrugs-08-02212f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/7ba2a55b57b9/marinedrugs-08-02212f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/6c0931de0f25/marinedrugs-08-02212f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/8b6d0902389d/marinedrugs-08-02212f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/9f58516574a3/marinedrugs-08-02212f4a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/32a5a2bf4f0e/marinedrugs-08-02212f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/165a87606306/marinedrugs-08-02212f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/7ba2a55b57b9/marinedrugs-08-02212f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/6c0931de0f25/marinedrugs-08-02212f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/8b6d0902389d/marinedrugs-08-02212f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/9f58516574a3/marinedrugs-08-02212f4a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/32a5a2bf4f0e/marinedrugs-08-02212f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae49/2920552/165a87606306/marinedrugs-08-02212f6.jpg

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