女性痤疮的激素治疗
Hormonal treatment of acne in women.
作者信息
Ebede Tobechi L, Arch Emily L, Berson Diane
出版信息
J Clin Aesthet Dermatol. 2009 Dec;2(12):16-22.
Abstract
Acne vulgaris is a common and chronic disorder of the pilosebaceous unit. Standard treatment protocols include topical retinoids, topical and oral antimicrobials, and isotretinoin. Hormonal therapies can be added to the regimen in some patients. This article will review the hormonal pathogenesis of acne, discuss the basics of an endocrine evaluation, and provide an overview of the current hormonal treatment options in women.
摘要
寻常痤疮是一种常见的毛囊皮脂腺慢性疾病。标准治疗方案包括外用维甲酸、外用和口服抗菌药物以及异维甲酸。在某些患者中，可在治疗方案中添加激素疗法。本文将综述痤疮的激素发病机制，讨论内分泌评估的基础知识，并概述目前女性的激素治疗选择。
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本文引用的文献
1
Pathogenesis of acne vulgaris: recent advances.寻常痤疮的发病机制：最新进展
J Drugs Dermatol. 2009 Jul;8(7):615-8.
2
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.痤疮管理的新见解：改善痤疮结局全球联盟小组的最新进展
J Am Acad Dermatol. 2009 May;60(5 Suppl):S1-50. doi: 10.1016/j.jaad.2009.01.019.
3
Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne.螺内酯对比安慰剂或联合类固醇治疗多毛症和/或痤疮。
Cochrane Database Syst Rev. 2009 Apr 15(2):CD000194. doi: 10.1002/14651858.CD000194.pub2.
4
Treatment of acne using a 3-milligram drospirenone/20-microgram ethinyl estradiol oral contraceptive administered in a 24/4 regimen: a randomized controlled trial.采用每片含3毫克屈螺酮/20微克炔雌醇的口服避孕药以24/4方案治疗痤疮：一项随机对照试验。
Obstet Gynecol. 2008 Oct;112(4):773-81. doi: 10.1097/AOG.0b013e318187e1c5.
6
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Semin Cutan Med Surg. 2008 Sep;27(3):188-96. doi: 10.1016/j.sder.2008.06.002.
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Climacteric. 2008 Oct;11(5):355-63. doi: 10.1080/13697130802322848.
8
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