兔骨的中性金属蛋白酶。以不同酶的潜伏形式分离，这些酶激活后可降解胶原蛋白、明胶和蛋白聚糖。
Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans.
作者信息
Sellers A, Reynolds J J, Meikle M C
出版信息
Biochem J. 1978 May 1;171(2):493-6. doi: 10.1042/bj1710493.
Abstract
Rabbit bones in culture produce specific collagenase and neutral metallo-proteinase activity in latent forms that can be activated by either 4-aminophenylmercuric acetate or trypsin. Latent neutral metallo-proteinase activity was resolved by gel filtration into two enzymes, distinct from collagenase, that degrade gelatin and cartilage proteoglycans.
摘要
培养中的兔骨会产生特定的潜在形式的胶原酶和中性金属蛋白酶活性，这些活性可被乙酸对氨基苯汞或胰蛋白酶激活。潜在的中性金属蛋白酶活性通过凝胶过滤分离为两种不同于胶原酶的酶，它们可降解明胶和软骨蛋白聚糖。
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