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初级保健下腰痛患者预后不良的预后因素的贡献。

Contributions of prognostic factors for poor outcome in primary care low back pain patients.

机构信息

Arthritis Research UK Primary Care Centre, Keele University, UK.

出版信息

Eur J Pain. 2011 Mar;15(3):313-9. doi: 10.1016/j.ejpain.2010.07.008. Epub 2010 Aug 21.

Abstract

BACKGROUND

Back pain is common and some sufferers consult GPs, yet many sufferers develop persistent problems. Combining information on risk of persistence and prognostic indicator prevalence provides more information on potential intervention targets than risk estimates alone.

AIMS

To determine the proportion of primary care back pain patients with persistent problems whose outcome is related to measurable prognostic factors.

METHODS

Prospective cohort study of back pain patients (30-59 years) at five general practices in Staffordshire, UK (n=389). Baseline factors (demographic; episode duration; symptom severity; pain widespreadness; anxiety; depression; catastrophising; fear-avoidance; self-rated health) were assessed for their association with disabling and limiting pain after 12-months. The proportion of those with persistent problems whose outcome was related to each factor was calculated.

RESULTS

Prevalence of prognostic factors ranged from 23% to 87%. Strongest predictors were unemployment (adjusted relative risk (RR) 4.2; 95% CI 2.0, 8.5) and high pain intensity (4.1; 1.7, 9.9). The largest proportions of persistent problems were related to high pain intensity (68%; 95% CI 27, 87%) and unemployment (64%; 33, 82%). Combining these indicated that 85% of poor back pain outcome is related to these two factors. Poor self-rated health, functional disability, upper body pain and pain bothersomeness were related with outcome for over 40% of those with persistent problems.

CONCLUSIONS

Several factors increased risk of poor outcome in back pain patients, notably high pain and unemployment. These risks in combination with high prevalence of risk factors in this population distinguish factors that can help identify targets or sub-groups for intervention.

摘要

背景

背痛较为常见,一些患者会咨询全科医生,但许多患者会出现持续性问题。将持续性风险信息与预后指标的流行情况相结合,提供的潜在干预目标信息比仅进行风险估计更为全面。

目的

确定有持续性问题的初级保健腰痛患者中,其结局与可测量预后因素相关的比例。

方法

对英国斯塔福德郡五家全科诊所的腰痛患者(30-59 岁)进行前瞻性队列研究(n=389)。基线因素(人口统计学;发病持续时间;症状严重程度;疼痛广泛性;焦虑;抑郁;灾难化;回避恐惧;自我评定健康)评估与 12 个月后致残性和限制疼痛相关。计算有持续性问题患者中,结局与每个因素相关的比例。

结果

预后因素的患病率范围为 23%至 87%。最强的预测因素是失业(调整后的相对风险(RR)4.2;95%可信区间(CI)2.0,8.5)和高疼痛强度(4.1;1.7,9.9)。与持续性问题相关的最大比例是高疼痛强度(68%;95%CI 27,87%)和失业(64%;33,82%)。结合这两个因素,85%的腰痛预后不良与这两个因素有关。自我评定健康状况差、功能障碍、上半身疼痛和疼痛困扰与持续性问题患者中 40%以上的结局相关。

结论

一些因素增加了腰痛患者不良结局的风险,特别是高疼痛和失业。这些风险与该人群中高患病率的风险因素相结合,可以帮助确定干预的目标或亚组。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04a5/3062783/a02f03ea1485/gr1.jpg

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