Arthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire, UK.
J Pain. 2013 Aug;14(8):873-83. doi: 10.1016/j.jpain.2013.03.013. Epub 2013 Jun 20.
Back pain is common and many people experience long-term problems, yet little is known about what prognostic factors predict long-term outcomes. This study's objective was to determine which factors predict short- and long-term outcomes in primary care consulters with low back pain (LBP). Analysis was carried out on 488 patients who had consulted their physician about LBP. Patients were followed up at 6 months and 5 years. Clinically significant LBP at follow-up was defined as a score of 2, 3, or 4 on the Chronic Pain Grade, indicating substantial pain and disability. Cox regression was used to estimate relative risks (RRs) with 95% confidence intervals (CIs) on 32 potential predictive factors, organized into domains (demographic, physical, psychological, and occupational). Baseline pain intensity conferred a 12% increase in risk (RR = 1.12, 95% CI = 1.03-1.20), and patients' belief that their LBP would persist conferred a 4% increase in risk (RR = 1.04, 95% CI = 1.01-1.07) for poor outcome at 6 months. Outcome at 5 years was best predicted by a model with the same factors as in the 6-month model: pain intensity increased risk by 9% (RR = 1.09, 95% CI = .997-1.20), and a belief that their LBP would persist increased risk by 6% (RR = 1.06, 95% CI = 1.03-1.09). Both predictors have the potential to be targets for clinical intervention.
Few studies have investigated factors that predict long-term back pain. This study has shown that pain intensity experienced during a period of primary care consultation, and patients' perception about whether their back pain will persist, were significant predictors of poor outcome at 6 months and at 5 years.
背痛很常见,很多人都有长期的问题,但对于哪些预后因素可以预测长期结果知之甚少。本研究的目的是确定哪些因素可以预测初级保健就诊者腰痛(LBP)的短期和长期结局。对 488 名因 LBP 咨询医生的患者进行了分析。患者在 6 个月和 5 年时进行了随访。在随访时,如果慢性疼痛等级得分为 2、3 或 4,则定义为临床显著的 LBP,表明有明显的疼痛和残疾。使用 Cox 回归估计 32 个潜在预测因素(分为人口统计学、身体、心理和职业)的相对风险(RR)和 95%置信区间(CI)。基线疼痛强度使风险增加 12%(RR=1.12,95%CI=1.03-1.20),患者认为自己的 LBP 会持续存在使风险增加 4%(RR=1.04,95%CI=1.01-1.07),则 6 个月时的不良结局。5 年的结局最好由与 6 个月模型相同的因素的模型来预测:疼痛强度使风险增加 9%(RR=1.09,95%CI=0.997-1.20),认为自己的 LBP 会持续存在使风险增加 6%(RR=1.06,95%CI=1.03-1.09)。这两个预测因素都有可能成为临床干预的目标。
很少有研究调查预测长期背痛的因素。本研究表明,在初级保健就诊期间经历的疼痛强度,以及患者对自己的背痛是否会持续存在的看法,是 6 个月和 5 年时不良结局的重要预测因素。