School of Biological and Chemical Sciences, Queen Mary, University of London, Mile End Road, London E1 4NS, UK.
Bioinformatics. 2010 Oct 15;26(20):2624-5. doi: 10.1093/bioinformatics/btq480. Epub 2010 Aug 24.
The defined secondary structure of proteins method is often considered the gold standard for assignment of secondary structure from three-dimensional coordinates. However, there are alternative methods. '2Struc: The Secondary Structure Server' has been created as a single point of access for eight different secondary structure assignment methods. It has been designed to enable comparisons between methods for analyzing the secondary structure content for a single protein. It also includes a second functionality, 'Compare-the-Protein' to enable comparisons of the secondary structure features from any one method to be made within a collection of nuclear magnetic resonance models, or between the crystal structures of two different proteins.
Supplementary data are available at Bioinformatics online.
蛋白质的二级结构定义方法通常被认为是从三维坐标分配二级结构的黄金标准。但是，还有其他替代方法。“2Struc：二级结构服务器”已被创建为八个不同二级结构分配方法的单点访问。它旨在为分析单个蛋白质的二级结构内容的方法之间进行比较提供便利。它还包括第二个功能“Compare-the-Protein”，可在核磁共振模型集合中或在两个不同蛋白质的晶体结构之间，将任何一种方法的二级结构特征进行比较。
补充数据可在“Bioinformatics”在线获取。
