Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, Georg August University, 37077 Göttingen, Germany.
J Bacteriol. 2010 Nov;192(21):5850-1. doi: 10.1128/JB.00844-10. Epub 2010 Aug 27.
The circular genome sequence of the chemolithoautotrophic euryarchaeon Methanothermobacter marburgensis, with 1,639,135 bp, was determined and compared with that of Methanothermobacter thermautotrophicus. The genomes of the two model methanogens differ substantially in protein coding sequences, in insertion sequence (IS)-like elements, and in clustered regularly interspaced short palindromic repeats (CRISPR) loci.
化学自养古菌 Methanothermobacter marburgensis 的环状基因组序列全长 1,639,135 bp,现已测定并与 Methanothermobacter thermautotrophicus 的基因组序列进行了比较。这两个模式产甲烷菌的基因组在蛋白质编码序列、插入序列(IS)样元件和成簇规律间隔短回文重复(CRISPR)位点方面存在显著差异。