Department of Preventive Medicine, Division of Health Behavior Research, University of Southern California Keck School of Medicine, 2250 Alcazar Street, Los Angeles, CA 90033, USA.
Health Psychol. 2010 Sep;29(5):521-8. doi: 10.1037/a0020854.
Based on a maladaptive coping explanation, the relationship between major depression (MD) and obesity could be strong among nonsmokers, who may engage in unhealthy eating and sedentary behavior to cope with depression. By contrast, the MD-obesity association could be weak among smokers, who can use tobacco (instead of food or sedentary behavior) to cope with mood symptoms. This study examined smoking status and tobacco dependence as moderators of the MD-obesity link.
Correlational, cross-sectional population-based survey of 41,654 U.S. adults.
Obesity (body mass index [BMI] ≥30 kg/m2) and quantitative BMI value.
Current smoking status moderated the association between past-year MD and current obesity, as well as the link between MD and BMI value (ps ≤ .0001). MD predicted obesity and BMI among nonsmokers (ps < .0001) but did not do so in smokers (ps ≥ .10). Similar findings emerged with tobacco dependence as the moderator. Each finding persisted after accounting for demographics, psychiatric variables, and potential confounds.
Tobacco use characteristics appear to moderate the MD-obesity association in the U.S. population. These findings may shed light on the mechanisms linking MD and obesity and have implications for identifying which individuals may benefit most from obesity interventions that target depressive symptoms. (PsycINFO Database Record (c) 2010 APA, all rights reserved).
基于适应不良应对的解释，在不吸烟者中，重度抑郁症（MD）与肥胖之间的关系可能很强，因为他们可能会通过不健康的饮食和久坐不动的行为来应对抑郁。相比之下，在吸烟者中，MD 与肥胖之间的关联可能较弱，因为他们可以使用烟草（而不是食物或久坐不动的行为）来应对情绪症状。本研究检验了吸烟状况和烟草依赖对 MD-肥胖关联的调节作用。
对 41654 名美国成年人进行了基于人口的横断面相关性研究。
肥胖（体重指数[BMI]≥30kg/m2）和定量 BMI 值。
当前吸烟状况调节了过去一年 MD 与当前肥胖之间的关联，以及 MD 与 BMI 值之间的联系（ps≤.0001）。MD 预测了非吸烟者的肥胖和 BMI（ps<.0001），但在吸烟者中则不然（ps≥.10）。用烟草依赖作为调节变量，也得出了类似的结果。在考虑了人口统计学变量、精神科变量和潜在混杂因素后，每个发现仍然存在。
在美国人群中，烟草使用特征似乎调节了 MD-肥胖的关联。这些发现可能揭示了将 MD 与肥胖联系起来的机制，并对确定哪些个体可能从针对抑郁症状的肥胖干预措施中获益最大具有启示意义。
