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伴有视觉功能障碍的视盘黑色素细胞瘤的特征

Characteristics of optic disc melanocytomas presenting with visual dysfunction.

作者信息

Al-Rashaed Saba, Abboud Emad B, Nowilaty Sawsan R

机构信息

Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

出版信息

Middle East Afr J Ophthalmol. 2010 Jul;17(3):242-5. doi: 10.4103/0974-9233.65488.

Abstract

OBJECTIVE AND DESIGN

A retrospective review study was designed to describe five cases of optic disc melanocytomas with tumor-related visual impairment.

PARTICIPANTS

Five patients with optic disc melanocytoma presented with visual complaints to a tertiary eye hospital in Saudi Arabia.

MATERIALS AND METHODS

Demographic and clinical data were analyzed, including the results of ocular examination, lesion laterality, best-corrected Snellen visual acuity, pupillary reflex, visual field testing, color fundus photography, fundus fluorescein angiography, and ophthalmic ultrasound.

RESULTS

Visual dysfunction secondary to optic disc melanocytoma was identified. Case 1 had macular star edema with mild tumor enlargement, Case 2 had optic atrophy, Case 3 had juxtapapillary choroidal neovascular membrane with macular involvement, Case 4 had optic disc swelling with an enlarged blind spot, and Case 5 had a large altitudinal visual field defect.

CONCLUSION

Although melanocytomas of the optic disc tend to have a benign behavior with slow evolution and stable vision, they may adversely affect visual function through a variety of mechanisms.

摘要

目的与设计

开展一项回顾性研究,以描述5例伴有肿瘤相关视力损害的视盘黑色素细胞瘤病例。

参与者

5例视盘黑色素细胞瘤患者因视力问题就诊于沙特阿拉伯一家三级眼科医院。

材料与方法

分析人口统计学和临床数据,包括眼科检查结果、病变部位、最佳矫正视力、瞳孔反射、视野检查、彩色眼底照相、眼底荧光血管造影和眼科超声检查结果。

结果

确定了视盘黑色素细胞瘤继发的视觉功能障碍。病例1出现黄斑星芒状水肿且肿瘤轻度增大,病例2出现视神经萎缩,病例3出现累及黄斑的视乳头旁脉络膜新生血管膜,病例4出现视盘肿胀且盲点扩大,病例5出现大片高度性视野缺损。

结论

尽管视盘黑色素细胞瘤通常表现为良性行为,发展缓慢且视力稳定,但它们可能通过多种机制对视功能产生不利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffc4/2934715/c623636964de/MEAJO-17-242-g001.jpg

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