Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Fisciano (Salerno), Italy.
Molecules. 2010 Sep 21;15(9):6630-7. doi: 10.3390/molecules15096630.
Monoterpenes, the main constituents of essential oils, are known for their many biological activities. The present work studied the potential biological activity of twenty-seven monoterpenes, including monoterpene hydrocarbons and oxygenated ones, against seed germination and subsequent primary radicle growth of Raphanus sativus L. (radish) and Lepidium sativum L. (garden cress), under laboratory conditions. The compounds, belonging to different chemical classes, showed different potency in affecting both parameters evaluated. The assayed compounds demonstrated a good inhibitory activity in a dose-dependent way. In general, radish seed is more sensitive than garden cress and its germination appeares more inhibited by alcohols; at the highest concentration tested, the more active substances were geraniol, borneol, (±)-β-citronellol and α-terpineol. Geraniol and carvone inhibited, in a significant way, the germination of garden cress, at the highest concentration tested. Radicle elongation of two test species was inhibited mainly by alcohols and ketones. Carvone inhibited the radicle elongation of both seeds, at almost all concentrations assayed, while 1,8-cineole inhibited their radicle elongation at the lowest concentrations (10(-5) M, 10(-6) M).
单萜类化合物是精油的主要成分，以其多种生物活性而闻名。本研究在实验室条件下，研究了 27 种单萜类化合物（包括单萜烃类和含氧单萜类）对萝卜（萝卜）和芝麻菜（芝麻菜）种子萌发及随后的初生主根生长的潜在生物活性。属于不同化学类别的化合物在影响两种被评估参数方面表现出不同的效力。所测试的化合物表现出良好的抑制活性，呈剂量依赖性。一般来说，萝卜种子比芝麻菜种子更敏感，其发芽似乎更易受醇类抑制；在测试的最高浓度下，更活跃的物质是香叶醇、龙脑、(±)-β-香茅醇和α-松油醇。在测试的最高浓度下，香叶醇和香芹酮显著抑制了芝麻菜的发芽。两种受试物种的主根伸长主要受到醇类和酮类的抑制。香芹酮几乎抑制了所有测试浓度的两种种子的主根伸长，而 1,8-桉叶素在最低浓度（10（-5）M、10（-6）M）下抑制了它们的主根伸长。
