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深海嗜热噬菌体 D6E 的基因组分析。

Genome analysis of deep-sea thermophilic phage D6E.

机构信息

Key Laboratory of Conservation Biology for Endangered Wildlife, Ministry of Education and College of Life Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.

出版信息

Appl Environ Microbiol. 2010 Dec;76(23):7861-6. doi: 10.1128/AEM.01270-10. Epub 2010 Oct 1.

DOI:10.1128/AEM.01270-10
PMID:20889772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2988599/
Abstract

In deep-sea hydrothermal vent communities, viruses play very important roles. However vent thermophilic bacteriophages remain largely unexplored. In this investigation, a novel vent Geobacillus bacteriophage, D6E, was characterized. Based on comparative genomics and proteomics analyses, the results showed an extensive mosaicism of D6E genome with other mesophilic or thermophilic phages.

摘要

在深海热液喷口群落中,病毒起着非常重要的作用。然而,热液嗜热噬菌体在很大程度上仍未被探索。在这项研究中,对一种新型喷口地芽孢杆菌噬菌体 D6E 进行了特征描述。基于比较基因组学和蛋白质组学分析,结果表明 D6E 基因组与其他中温或高温噬菌体存在广泛的嵌合体现象。

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本文引用的文献

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Proteomic analysis of interactions between a deep-sea thermophilic bacteriophage and its host at high temperature.深海嗜热噬菌体与其宿主在高温下相互作用的蛋白质组学分析。
J Virol. 2010 Mar;84(5):2365-73. doi: 10.1128/JVI.02182-09. Epub 2009 Dec 16.
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Viruses manipulate the marine environment.病毒操控着海洋环境。
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Identification and characterization of a novel thymidylate synthase from deep-sea thermophilic bacteriophage Geobacillus virus E2.来自深海嗜热噬菌体嗜热栖热放线杆菌病毒E2的一种新型胸苷酸合成酶的鉴定与表征
Virus Genes. 2008 Oct;37(2):218-24. doi: 10.1007/s11262-008-0258-5. Epub 2008 Jul 22.
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Deep-sea thermophilic Geobacillus bacteriophage GVE2 transcriptional profile and proteomic characterization of virions.深海嗜热栖热放线菌噬菌体GVE2的转录谱及病毒粒子的蛋白质组学特征
Appl Microbiol Biotechnol. 2008 Sep;80(4):697-707. doi: 10.1007/s00253-008-1575-2. Epub 2008 Jul 18.
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Genome comparison and proteomic characterization of Thermus thermophilus bacteriophages P23-45 and P74-26: siphoviruses with triplex-forming sequences and the longest known tails.嗜热栖热菌噬菌体P23 - 45和P74 - 26的基因组比较与蛋白质组学特征:具有三链形成序列和已知最长尾部的肌尾噬菌体
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