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真菌代谢产物多杀霉素的其他毒性特性。

Further toxic properties of the fungal metabolite dothistromin.

作者信息

Stoessl A, Abramowski Z, Lester H H, Rock G L, Towers G H

机构信息

Agriculture Canada, London Research Centre, Ontario, Canada.

出版信息

Mycopathologia. 1990 Dec;112(3):179-86. doi: 10.1007/BF00436652.

DOI:10.1007/BF00436652
PMID:2089260
Abstract

The toxicity of the fungal phytotoxin dothistromin (l) to microorganisms, its lysis of human red blood corpuscles and beetroot tissue, and its unexpectedly selective inhibition of radicle elongation for Trigonella foenum-graecum were strongly light-dependent. Dothistromin was also toxic to Artemia salina but without requiring light activation. It was not active as a wilt or necrosis toxin, possible because of its ready adsorption onto external plant tissue.

摘要

真菌植物毒素多杀霉素(l)对微生物的毒性、其对人红细胞和甜菜根组织的裂解作用,以及其对胡芦巴胚根伸长的意外选择性抑制作用均强烈依赖于光照。多杀霉素对卤虫也有毒性,但不需要光激活。它作为一种萎蔫或坏死毒素没有活性,可能是因为它易于吸附到植物外部组织上。

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Further toxic properties of the fungal metabolite dothistromin.真菌代谢产物多杀霉素的其他毒性特性。
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2
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本文引用的文献

1
Changes in tobacco cell membrane composition and structure caused by cercosporin.麦角甾醇生物合成抑制剂对烟草细胞膜组成和结构的影响。
Plant Physiol. 1983 Apr;71(4):763-6. doi: 10.1104/pp.71.4.763.
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Phototoxic furanoquinolines of the Rutaceae.芸香科的光毒性呋喃喹啉类化合物。
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3
Brine shrimp: a convenient general bioassay for active plant constituents.卤虫:一种用于活性植物成分的便捷通用生物测定法。
Toxins (Basel). 2010 Dec;2(12):2738-53. doi: 10.3390/toxins2122738. Epub 2010 Nov 29.
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Genetics of dothistromin biosynthesis of Dothistroma septosporum: an update.球腔菌属Septosporium dothistroma 中多脱氧间型霉素生物合成的遗传学:更新。
Toxins (Basel). 2010 Nov;2(11):2680-98. doi: 10.3390/toxins2112680. Epub 2010 Nov 5.
5
Functional analysis of a putative Dothistromin toxin MFS transporter gene.推测的长松萝毒素 MFS 转运蛋白基因的功能分析。
Toxins (Basel). 2009 Dec;1(2):173-87. doi: 10.3390/toxins1020173. Epub 2009 Dec 8.
6
Identification of a hybrid PKS-NRPS required for the biosynthesis of NG-391 in Metarhizium robertsii.鉴定罗伯茨青霉菌生物合成 NG-391 所需的杂合 PKS-NRPS。
Curr Genet. 2010 Apr;56(2):151-62. doi: 10.1007/s00294-010-0288-0. Epub 2010 Feb 7.
7
Dothistroma pini, a forest pathogen, contains homologs of aflatoxin biosynthetic pathway genes.松针散斑壳,一种森林病原体,含有黄曲霉毒素生物合成途径基因的同源物。
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Planta Med. 1982 May;45(1):31-4.
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Dothistromin as a metabolite of Cercospora arachidicola.多杀霉素作为落花生尾孢菌的一种代谢产物。
Mycopathologia. 1984 Jun 30;86(3):165-8. doi: 10.1007/BF00441127.
5
Photoimmunotherapy: treatment of animal tumors with tumor-specific monoclonal antibody-hematoporphyrin conjugates.光免疫疗法:用肿瘤特异性单克隆抗体-血卟啉偶联物治疗动物肿瘤。
J Immunol. 1983 Mar;130(3):1473-7.
6
Chromosome damage by dothistromin in human peripheral blood lymphocyte cultures: a comparison with aflatoxin B1.多毛孢素对人外周血淋巴细胞培养物中染色体的损伤:与黄曲霉毒素B1的比较。
Mutat Res. 1986 Apr-May;170(1-2):47-53. doi: 10.1016/0165-1218(86)90081-9.
7
Increased frequency of sister-chromatid exchange induced by dothistromin in CHO cells and human lymphocytes.多杀霉素在CHO细胞和人淋巴细胞中诱导姐妹染色单体交换频率增加。
Mutat Res. 1989 Mar;222(3):167-70. doi: 10.1016/0165-1218(89)90133-x.
8
Multiple modes of photodynamic action by cercosporin.尾孢菌素的多种光动力作用模式。
Photochem Photobiol. 1988 May;47(5):699-703. doi: 10.1111/j.1751-1097.1988.tb02767.x.
9
Some biological properties of traversianal, a strongly molluscicidal diterpenoid aldehyde from Cercospora traversiana.横梗孢醛的一些生物学特性,一种来自横梗尾孢菌的强杀软体动物二萜醛。
Mycopathologia. 1989 Apr;106(1):41-6. doi: 10.1007/BF00436925.
10
Inhibition of RNA synthesis in Chlorella pyrenoidosa and Bacillus megaterium by the pine-blight toxin, dothistromin.
J Gen Microbiol. 1976 Aug;96(2):268-76. doi: 10.1099/00221287-95-2-268.