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[Studies on the chemical constituents of Rhynchotechum vestitum Hook. F. et Thoms].

作者信息

Liu G M, Chen Z N, Yao T R, Ding W G

机构信息

Department of Chemistry, Shanghai Second Medical University.

出版信息

Yao Xue Xue Bao. 1990;25(9):699-704.

PMID:2092579
Abstract

Rhynchotechum vestitum Hook, F. et Thoms. mainly distributed in the southern part of Yunnan Province of China, has been used as a folk remedy for the treatment of hepatitis. No information has been found in the literature about its chemical investigation. In this paper, five compounds isolated from the ethanol extract of the stem and root of the plant are reported. Four of them were identified as beta-sitosterol (I), lupeol (II), rubiadin 1-methylether (III) and rubiadin (IV). The fifth, an orange needle crystal (C17H14O6, mp 236, 5-238 degrees C) is a new anthraquinone compound named rhynchotechol. Its structure has been proved to be 1,6-dihydroxy-7,8-dimethoxy-2-methyl-9,10-anthraquinone by spectral analyses and chemical methods.

摘要

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Chemistry, Biosynthesis, Physicochemical and Biological Properties of Rubiadin: A Promising Natural Anthraquinone for New Drug Discovery and Development.茜素:一种有前途的天然蒽醌,用于新药发现和开发的化学、生物合成、物理化学和生物学特性。
Drug Des Devel Ther. 2021 Nov 3;15:4527-4549. doi: 10.2147/DDDT.S338548. eCollection 2021.