Expert Opin Drug Deliv. 2010 Nov;7(11):1235-8. doi: 10.1517/17425247.2010.525231. Epub 2010 Oct 12.
Recent reviews conclude that there is a need to improve the management of respiratory diseases treated with inhaled drugs, mainly asthma and chronic obstructive pulmonary disease (COPD). Healthcare professionals - mainly in primary care - seem to lack to some degree the evidence-based information required for the selection of the most appropriate respiratory drug delivery devices (inhalers) for the patients, whereas some of the patients often tend to have poor inhaler technique. This could have an impact on the ability to control the respiratory diseases in question. There are probably several reasons for these apparent challenges in the primary care arena. Owing to the abundance of inhalers available at present, especially for the treatment of asthma and COPD, it is quite a challenge to pick the 'right' inhaler for each patient. For an inhaler to be optimal, the patient has to be able to master the inhaler technique required for the specific inhaler. The patient-inhaler interfaces - mouthpieces or facemasks - can add important challenges that further diminish the efficacy of the treatment.
最近的评论得出结论，需要改进吸入药物治疗的呼吸系统疾病的管理，主要是哮喘和慢性阻塞性肺疾病（COPD）。医疗保健专业人员 - 主要是在初级保健中 - 似乎在某种程度上缺乏为患者选择最合适的呼吸药物输送装置（吸入器）所需的基于证据的信息，而有些患者往往吸入器技术较差。这可能会影响控制所涉及的呼吸系统疾病的能力。对于初级保健领域的这些明显挑战，可能有几个原因。由于目前可用的吸入器数量众多，特别是用于治疗哮喘和 COPD，因此为每位患者选择“合适”的吸入器是一项挑战。为了使吸入器达到最佳效果，患者必须能够掌握特定吸入器所需的吸入器技术。患者 - 吸入器接口 - 口件或面罩 - 可能会增加进一步降低治疗效果的重要挑战。
