代谢组学与疟疾生物学
Metabolomics and malaria biology.
作者信息
Lakshmanan Viswanathan, Rhee Kyu Y, Daily Johanna P
机构信息
Department of Medicine, Infectious Diseases Division, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, USA.
出版信息
Mol Biochem Parasitol. 2011 Feb;175(2):104-11. doi: 10.1016/j.molbiopara.2010.09.008. Epub 2010 Oct 21.
Abstract
Metabolomics has ushered in a novel and multi-disciplinary realm in biological research. It has provided researchers with a platform to combine powerful biochemical, statistical, computational, and bioinformatics techniques to delve into the mysteries of biology and disease. The application of metabolomics to study malaria parasites represents a major advance in our approach towards gaining a more comprehensive perspective on parasite biology and disease etiology. This review attempts to highlight some of the important aspects of the field of metabolomics, and its ongoing and potential future applications to malaria research.
摘要
代谢组学在生物学研究中开创了一个全新的多学科领域。它为研究人员提供了一个平台，可结合强大的生化、统计、计算和生物信息学技术，深入探究生物学和疾病的奥秘。代谢组学在研究疟原虫方面的应用代表了我们在更全面了解寄生虫生物学和疾病病因学的方法上取得的重大进展。本综述旨在突出代谢组学领域的一些重要方面，以及其在疟疾研究中的现有和潜在未来应用。
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