Tsukuba University of Technology, Ibaraki, Japan.
Med Sci Sports Exerc. 2011 Jun;43(6):967-73. doi: 10.1249/MSS.0b013e3182019774.
To investigate the effect of menstrual cycle states on ovarian and anabolic hormonal responses to acute resistance exercise in young women.
Eight healthy women (eumenorrhea; EM) and eight women with menstrual disorders including oligomenorrhea and amenorrhea (OAM) participated in this study. The EM group performed acute resistance exercises during the early follicular (EF) and midluteal (ML) phases, and the OAM group performed the same exercises. All subjects performed three sets each of lat pull-downs, leg curls, bench presses, leg extensions, and squats at 75%-80% of one-repetition maximum with a 1-min rest between sets. Blood samples were obtained before exercise, immediately after, 30 min after, and 60 min after the exercise.
In the EM group, resting serum levels of estradiol and progesterone in the ML phase were higher than those in the EF phase and higher than those in the OAM group. Serum estradiol and progesterone in the ML phase increased after the exercise but did not change in the EF phase or in the OAM group. In contrast, resting levels of testosterone in the OAM group were higher than those in both the ML and EF phases of the EM group. After the exercise, serum growth hormone increased in both the ML and EF phases but did not change in the OAM group.
The responses of anabolic hormones to acute resistance exercise are different among the menstrual cycle states in young women. Women with menstrual disturbances with low estradiol and progesterone serum levels have an attenuated anabolic hormone response to acute resistance exercise, suggesting that menstrual disorders accompanying low ovarian hormone levels may affect exercise-induced change in anabolic hormones in women.
研究月经周期状态对年轻女性急性抗阻运动时卵巢和合成代谢激素反应的影响。
本研究纳入 8 名健康的月经正常女性（月经正常组，EM）和 8 名患有月经失调（包括月经稀发和闭经）的女性（月经失调组，OAM）。EM 组在卵泡早期（EF）和黄体中期（ML）进行急性抗阻运动，OAM 组则在相同阶段进行运动。所有受试者在每组之间休息 1 分钟的情况下，以 75%-80%的 1 次重复最大强度进行 3 组每组的下拉练习、腿弯举、卧推、腿伸展和深蹲。在运动前、运动后即刻、运动后 30 分钟和 60 分钟采集血样。
在 EM 组中，ML 期的血清雌二醇和孕酮基础水平高于 EF 期，且高于 OAM 组。运动后 ML 期的血清雌二醇和孕酮增加，但 EF 期或 OAM 组没有变化。相反，OAM 组的血清睾酮基础水平高于 EM 组的 ML 和 EF 期。运动后，ML 和 EF 期的血清生长激素均增加，但 OAM 组没有变化。
年轻女性在不同月经周期状态下对急性抗阻运动的合成代谢激素反应不同。伴有低雌二醇和孕酮血清水平的月经失调女性对急性抗阻运动的合成代谢激素反应减弱，提示伴随低卵巢激素水平的月经失调可能影响女性运动诱导的合成代谢激素变化。
