Université d'Évry Val d'Essonne, École doctorale des Génomes Aux Organismes, Boulevard François Mitterrand, F-91025 Evry cedex, France.
J Control Release. 2011 Feb 10;149(3):209-24. doi: 10.1016/j.jconrel.2010.09.023. Epub 2010 Oct 28.
Cell microcarriers and microcapsules have presented a wide range of potential applications. This article overviews their role in biotechnology with focus on the progress accomplished using stimuli-responsive polymers. Key properties of cell microcarriers and microcapsules are identified, followed by a description of the chemistry and gel formation mechanism of some of the stimuli-responsive polymers used to design them. Production methods are introduced and characterization techniques for evaluating such microsystems are equally presented.
细胞微载体和微胶囊具有广泛的潜在应用。本文综述了它们在生物技术中的作用，重点介绍了使用响应性聚合物取得的进展。确定了细胞微载体和微胶囊的关键性质，接着描述了用于设计这些微载体和微胶囊的一些响应性聚合物的化学和凝胶形成机制。介绍了它们的生产方法，并同样提出了用于评估此类微系统的表征技术。
