Department of Nutrition, Hospitality, and Retailing, Texas Tech University, PO Box 41240, Lubbock, TX 79409, USA.
Appetite. 2011 Feb;56(1):171-8. doi: 10.1016/j.appet.2010.10.009. Epub 2010 Oct 28.
To compare the effects of both dietary fatty acid composition and exercise vs. sedentary conditions on circulating levels of hunger and satiety hormones. Eight healthy males were randomized in a 2 × 2 crossover design. The four treatments were 3 days of HF diets (50% of energy) containing high saturated fat (22% of energy) with exercise (SE) or sedentary (SS) conditions, and high monounsaturated fat (30% of energy) with exercise (UE) or sedentary (US) conditions. Cycling exercise was completed at 45% of VO(2)max for 2h daily. On the third HF day, 20 blood samples were drawn over a 24h period for each hormone (leptin, insulin, ghrelin, and peptide YY (PYY)). A visual analog scale (VAS) was completed hourly between 0800 and 2200. Average 24h leptin and insulin levels were lower while 24h PYY was higher during exercise vs. sedentary conditions. FA composition did not differentially affect 24h hormone values. VAS scores for hunger and fullness did not differ between any treatment but did correlate with ghrelin, leptin, and insulin. High saturated or unsaturated fat diets did not differ with respect to markers of hunger or satiety. Exercise decreased 24h leptin and insulin while increasing PYY regardless of FA composition.
比较饮食脂肪酸组成和运动与久坐对饥饿和饱腹感激素循环水平的影响。8 名健康男性按 2×2 交叉设计随机分组。四种处理方式为：3 天高饱和脂肪（占能量的 22%）高脂肪饮食（占能量的 50%）结合运动（SE）或久坐（SS）条件，以及高单不饱和脂肪（占能量的 30%）结合运动（UE）或久坐（US）条件。每日进行 2 小时 45%最大摄氧量的自行车运动。在第 3 天的 HF 日，在每个激素（瘦素、胰岛素、胃饥饿素和肽 YY（PYY））的 24 小时内抽取 20 个血液样本。在 0800 到 2200 之间，每小时完成一个视觉模拟量表（VAS）。与久坐相比，运动时平均 24 小时瘦素和胰岛素水平较低，而 PYY 则较高。FA 组成不会对 24 小时激素值产生差异影响。VAS 评分在任何治疗之间饥饿和饱腹感没有差异，但与胃饥饿素、瘦素和胰岛素相关。高饱和或不饱和脂肪饮食在饥饿或饱腹感标志物方面没有差异。运动降低了 24 小时的瘦素和胰岛素水平，同时增加了 PYY，而与 FA 组成无关。
