Pediatrics Department, Municipal Hospital Neustadt, Dresden, Germany.
Digestion. 2011;83(1-2):76-82. doi: 10.1159/000320455. Epub 2010 Oct 30.
Prevalence data of hepatitis B virus (HBV) in pregnant women in the Eastern part of Germany are missing. More importantly, no data on HBV's impact on pregnancy is known in patients living in the Western hemisphere. Our aim was to assess the prevalence of hepatitis B surface antigen (HBsAg) and its impact on pregnancy in women admitted to the department of gynecology at a German university hospital.
8,193 women who delivered at the university hospital between 2001 and 2006 were retrospectively screened for HBsAg and if positive investigated for pregnancy and newborn complications in comparison to women without hepatitis B infection.
39 (0.48%) women were found to be HBsAg carriers, which is in line with other data showing lower rates in Eastern parts of Germany in relation to the Western part. Furthermore, prevalence was much lower in German-born women (0.2%) in comparison to Asian-born women (9.1%). Secondly, women with HBsAg had no significantly increased prevalence of adverse pregnancy outcomes.
There is a low prevalence of HBV infection, especially among German-born women. There is no significant evidence to support increased complications in relation to HBV infection in our study.
在德国东部，关于孕妇乙型肝炎病毒（HBV）流行的数据尚属空白。更重要的是，在西半球，我们还不知道 HBV 对妊娠的影响。我们的目的是评估在德国一所大学医院妇产科就诊的女性中乙肝表面抗原（HBsAg）的流行率及其对妊娠的影响。
对 2001 年至 2006 年间在该大学医院分娩的 8193 名妇女进行了回顾性筛查，以检测 HBsAg，并对阳性妇女进行妊娠和新生儿并发症的调查，与未感染乙型肝炎的妇女进行比较。
39 名（0.48%）妇女为 HBsAg 携带者，这与其他数据一致，表明德国东部的 HBV 感染率低于西部。此外，德国出生的妇女（0.2%）的 HBsAg 流行率明显低于亚洲出生的妇女（9.1%）。其次，HBsAg 阳性妇女的不良妊娠结局发生率并无显著增加。
HBV 感染率较低，尤其是在德国出生的妇女中。在我们的研究中，没有证据表明 HBV 感染与并发症增加有关。
