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探讨口服避孕药在痤疮治疗中的应用。

Examining the use of oral contraceptives in the management of acne.

机构信息

Departments of Dermatology and.

出版信息

Int J Womens Health. 2010 Aug 9;2:69-76. doi: 10.2147/ijwh.s5915.

DOI:10.2147/ijwh.s5915
PMID:21072299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2971728/
Abstract

Combined oral contraceptive pills (cOCPs) are often used in the treatment of acne in females. They are effective, safe, and easy to use in appropriate patients in combination with more conventional acne therapies. This article will briefly address the physiologic rationale for the use of cOCPs in the treatment of acne. It will also review efficacy by examining relevant clinical trials. Safety considerations and the adverse event profile for oral contraceptives will be presented. Finally, practical considerations for prescribing cOCPs will be discussed.

摘要

口服避孕药(COCP)常用于女性痤疮的治疗。在适当的患者中,COCP 联合更常规的痤疮治疗方法,具有疗效好、安全性高、使用方便的特点。本文将简要介绍 COCP 治疗痤疮的生理基础,并通过相关临床试验评估其疗效。本文还将介绍口服避孕药的安全性考虑因素和不良事件概况。最后,将讨论 COCP 处方的实际注意事项。

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本文引用的文献

1
Combined oral contraceptive pills for treatment of acne.复方口服避孕药治疗痤疮。
Cochrane Database Syst Rev. 2009 Jul 8(3):CD004425. doi: 10.1002/14651858.CD004425.pub4.
2
Combined hormonal contraception and venous thromboembolism.复方激素避孕与静脉血栓栓塞
Eur J Contracept Reprod Health Care. 2007 Jun;12(2):97-106. doi: 10.1080/13625180701300194.
3
Initiation of oral contraceptives using a quick start compared with a conventional start: a randomized controlled trial.与传统起始方式相比,采用快速启动法开始使用口服避孕药:一项随机对照试验。
Obstet Gynecol. 2007 Jun;109(6):1270-6. doi: 10.1097/01.AOG.0000264550.41242.f2.
4
The safety of a drospirenone-containing oral contraceptive: final results from the European Active Surveillance Study on oral contraceptives based on 142,475 women-years of observation.含屈螺酮口服避孕药的安全性:基于142475女性年观察数据的欧洲口服避孕药主动监测研究的最终结果
Contraception. 2007 May;75(5):344-54. doi: 10.1016/j.contraception.2006.12.019. Epub 2007 Feb 23.
5
Oral contraceptives and breakthrough bleeding: what patients need to know.口服避孕药与突破性出血:患者需要了解的内容。
J Fam Pract. 2006 Oct;55(10):872-80.
6
Biphasic versus triphasic oral contraceptives for contraception.用于避孕的双相口服避孕药与三相口服避孕药
Cochrane Database Syst Rev. 2006 Jul 19;2006(3):CD003283. doi: 10.1002/14651858.CD003283.pub2.
7
Initiating hormonal contraception.
Am Fam Physician. 2006 Jul 1;74(1):105-12.
8
Deep vein thrombosis and pulmonary embolism reported in the Prescription Event Monitoring Study of Yasmin.在Yasmin处方事件监测研究中报告的深静脉血栓形成和肺栓塞。
Br J Clin Pharmacol. 2005 Jul;60(1):98-102. doi: 10.1111/j.1365-2125.2005.02373.x.
9
Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function.前沿:全反式维甲酸下调Toll样受体2(TLR2)的表达及功能。
J Immunol. 2005 Mar 1;174(5):2467-70. doi: 10.4049/jimmunol.174.5.2467.
10
"Quick Start", an innovative approach to the combination oral contraceptive pill in adolescents. Is it time to make the switch?
J Pediatr Adolesc Gynecol. 2004 Feb;17(1):65-7. doi: 10.1016/j.jpag.2003.11.005.