Institute of Cardiovascular Sciences, St Boniface Hospital Research Centre and Department of Physiology, University of Manitoba, Winnipeg, Manitoba.
Can J Cardiol. 2010 Nov;26(9):489-96. doi: 10.1016/s0828-282x(10)70455-4.
Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a therapeutic strategy that may warrant greater research attention. The increased use of omega (ω)-3 fatty acids is a powerful example of one such nutritional strategy that may produce significant cardiovascular benefits. Marine food products have provided the traditional dietary sources of ω-3 fatty acids. Flaxseed is an alternative to marine products. It is one of the richest sources of the plant-based ω-3 fatty acid, alpha-linolenic acid (ALA). Based on the results of clinical trials, epidemiological investigations and experimental studies, ingestion of ALA has been suggested to have a positive impact on CVD. Because of its high ALA content, the use of flaxseed has been advocated to combat CVD. The purpose of the present review was to identify the known cardiovascular effects of flaxseed and ALA and, just as importantly, what is presently unknown.
通过营养干预预防心血管疾病（CVD）是一种值得进一步研究的治疗策略。增加 ω-3 脂肪酸的使用就是这样一种营养策略的一个有力例子，它可能会带来显著的心血管益处。海洋食品是 ω-3 脂肪酸的传统饮食来源。亚麻籽是海洋产品的替代品。它是植物性 ω-3 脂肪酸 α-亚麻酸（ALA）最丰富的来源之一。基于临床试验、流行病学调查和实验研究的结果，摄入 ALA 被认为对 CVD 有积极影响。由于其高 ALA 含量，亚麻籽的使用被提倡用于对抗 CVD。本综述的目的是确定已知的亚麻籽和 ALA 的心血管作用，同样重要的是，目前还不知道的是什么。
