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园艺作物中的基因组资源:现状、利用和挑战。

Genomic resources in horticultural crops: status, utility and challenges.

机构信息

National Research Centre on Plant Biotechnology, IARI, Pusa Campus, New Delhi, India.

出版信息

Biotechnol Adv. 2011 Mar-Apr;29(2):199-209. doi: 10.1016/j.biotechadv.2010.11.002. Epub 2010 Nov 19.

DOI:10.1016/j.biotechadv.2010.11.002
PMID:21094247
Abstract

A significant review of status and availability of genomic resources in horticultural crops can be utilized for the efficient exploitation of the current research in developing improved varieties and also defining future goals. In this review, we describe the current genomic resources available in major horticultural crops and utility of the genomic and genic sequence information for isolating and characterizing novel useful genes and designing new DNA markers. We have found that these genomic resources have been utilized for both basic and applied research; however the progress is relatively slow. Recent advances in automation and high throughput techniques used in decoding plant genomes play an important role to speed up the genomic research. With the establishment of genome and transcriptome sequencing projects for several horticultural crops, huge wealth of sequence information have been generated. These sequence information have been used extensively for analyzing and understanding genome structures and complexities, comparative and functional genomics and to mine useful genes and molecular markers. However, certain limitations present a number of challenges for the generation and utilization of genomic resources in many important crops.

摘要

对园艺作物基因组资源的现状和可用性进行的重要综述,可用于有效地利用当前的研究成果来开发改良品种,并确定未来的目标。在本综述中,我们描述了主要园艺作物中现有的基因组资源,以及基因组和基因序列信息在分离和鉴定新的有用基因和设计新的 DNA 标记方面的应用。我们发现,这些基因组资源已被用于基础研究和应用研究;然而,进展相对缓慢。在解码植物基因组中使用的自动化和高通量技术的最新进展,对于加快基因组研究起着重要作用。随着几个园艺作物的基因组和转录组测序项目的建立,产生了大量的序列信息。这些序列信息被广泛用于分析和理解基因组的结构和复杂性、比较和功能基因组学,并挖掘有用的基因和分子标记。然而,在许多重要作物中,基因组资源的产生和利用存在一定的局限性,这给它们带来了许多挑战。

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