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调查肯尼亚传统上用于治疗疟疾的一些药用植物,以寻找潜在的抗疟药物来源。

Investigation of some medicinal plants traditionally used for treatment of malaria in Kenya as potential sources of antimalarial drugs.

机构信息

Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute, P.O. Box 54840, Nairobi, Kenya.

出版信息

Exp Parasitol. 2011 Mar;127(3):609-26. doi: 10.1016/j.exppara.2010.11.004. Epub 2010 Nov 21.

Abstract

Malaria is a major public health problem in many tropical and subtropical countries and the burden of this disease is getting worse, mainly due to the increasing resistance of Plasmodium falciparum against the widely available antimalarial drugs. There is an urgent need for discovery of new antimalarial agents. Herbal medicines for the treatment of various diseases including malaria are an important part of the cultural diversity and traditions of which Kenya's biodiversity has been an integral part. Two major antimalarial drugs widely used today came originally from indigenous medical systems, that is quinine and artemisinin, from Peruvian and Chinese ancestral treatments, respectively. Thus ethnopharmacology is a very important resource in which new therapies may be discovered. The present review is an analysis of ethnopharmacological publications on antimalarial therapies from some Kenyan medicinal plants.

摘要

疟疾是许多热带和亚热带国家的主要公共卫生问题,而且这种疾病的负担越来越重,主要是由于恶性疟原虫对广泛使用的抗疟药物的耐药性不断增加。迫切需要发现新的抗疟药物。草药治疗各种疾病,包括疟疾,是肯尼亚生物多样性的文化多样性和传统的重要组成部分。目前广泛使用的两种主要抗疟药物最初来自土著医疗系统,即奎宁和青蒿素,分别来自秘鲁和中国的祖传疗法。因此,民族药理学是一个非常重要的资源,可以从中发现新的治疗方法。本综述分析了一些肯尼亚药用植物抗疟疗法的民族药理学出版物。

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