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黄酮类化合物的来源、毒性及生物活性的综合评述

A Compressive Review on Source, Toxicity and Biological Activity of Flavonoid.

机构信息

Department of Pharmacology, GLA University, NH#2 Delhi Mathura Highway, Uttar Pradesh, India.

出版信息

Curr Top Med Chem. 2024;24(24):2093-2116. doi: 10.2174/0115680266316032240718050055.

Abstract

Flavonoids are biologically active chemicals in various fruits, plants, vegetables, and leaves, which have promising uses in medicinal science. The health properties of these natural chemicals are widely accepted, and efforts are underway to extract the specific components referred to as flavonoids. Flavonoids demonstrate a diverse range of bio-activities, anticancer, antioxidant activity, anti-cholinesterase activity, antiinflammatory activity, antimalarial activity, antidiabetic activity, neurodegenerative disease, cardiovascular effect, hepatoprotective effects, and antiviral and antimicrobial activity. This study aims to examine the prevailing trends in flavonoid investigation studies, elucidate the activity of flavonoids, examine their various functions and uses, assess the potential of flavonoids as preventive medications for chronic diseases, and outline future research opportunities in this field. This review explores the diverse functions of flavonoids in preventing and managing various diseases.

摘要

类黄酮是各种水果、植物、蔬菜和叶子中的生物活性化学物质,在医学科学中有广泛的应用前景。这些天然化学物质的健康特性已被广泛认可,人们正在努力提取被称为类黄酮的特定成分。类黄酮表现出多种生物活性,如抗癌、抗氧化、抗胆碱酯酶、抗炎、抗疟、抗糖尿病、神经退行性疾病、心血管效应、保肝作用以及抗病毒和抗菌活性。本研究旨在探讨类黄酮研究的流行趋势,阐明类黄酮的活性,研究它们的各种功能和用途,评估类黄酮作为预防慢性病的潜在药物,并概述该领域的未来研究机会。本综述探讨了类黄酮在预防和治疗各种疾病方面的多种功能。

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