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天然草药物质的使用难点及其在某些药物剂型中的当前应用

Difficulties in Using Natural Herbal Substances and Their Current use in Some Pharmaceutical Dosage Forms.

作者信息

Bulbul Ece Ozcan, Okur Neslihan Ustundag

机构信息

Department of Pharmaceutical Technology, Faculty of Pharmacy, Istinye University, Istanbul, Turkey.

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Health Sciences, Istanbul, Turkey.

出版信息

Curr Pharm Des. 2025;31(28):2252-2266. doi: 10.2174/0113816128346715250120074519.

DOI:10.2174/0113816128346715250120074519
PMID:39950459
Abstract

AIM

Random use of natural herbal products affects the treatment of diseases. In this review, the limitations may be encountered in using natural substances of plant origin and the studies on using these substances in treating cancer, cognitive disorders, heart diseases, diabetes, and microbial diseases are examined and summarized.

BACKGROUND

People worldwide use herbal products derived from natural plants to solve health problems. It is known that random use of herbal products can negatively affect the treatment. However, people need help with the formulation or use of natural substances. There is no new disease-modifying herbal therapy available to treat diseases such as cancer, microbial disorders, diabetes, cognitive disorders, and cardiac disorders.

OBJECTIVE

This review aims to report the difficulties encountered in formulating and using natural herbal substances and highlight their possible use in some diseases.

MATERIALS AND METHODS

Available information about the study was collected through many search engines such as Science Direct, PubMed, and Google Scholar.

RESULTS

Working with natural herbal substances worldwide presents many difficulties, especially a lack of knowledge, modern technological devices, or clinical studies. According to currently available studies, some natural herbal substances are effective against cancer, microbial disorders, diabetes, cognitive disorders, and heart disorders.

CONCLUSION

Deepening the studies would be benefical in eliminating the difficulties related to natural herbal medicines and making them more reliable. More research is needed to include these substances in the protocol and use them in treating diseases.

摘要

目的

天然草药产品的随意使用会影响疾病治疗。在本综述中,探讨并总结了使用植物源性天然物质时可能遇到的局限性,以及关于这些物质用于治疗癌症、认知障碍、心脏病、糖尿病和微生物疾病的研究。

背景

世界各地的人们使用源自天然植物的草药产品来解决健康问题。众所周知,随意使用草药产品会对治疗产生负面影响。然而,人们在天然物质的配方或使用方面需要帮助。目前尚无新的改善病情的草药疗法可用于治疗癌症、微生物疾病、糖尿病、认知障碍和心脏疾病等。

目的

本综述旨在报告在天然草药物质的配方和使用中遇到的困难,并强调它们在某些疾病中的可能用途。

材料与方法

通过Science Direct、PubMed和谷歌学术等多个搜索引擎收集有关该研究的可用信息。

结果

在全球范围内使用天然草药物质存在许多困难,尤其是缺乏知识、现代技术设备或临床研究。根据目前可得的研究,一些天然草药物质对癌症、微生物疾病、糖尿病、认知障碍和心脏疾病有效。

结论

深入开展研究将有助于消除与天然草药相关的困难,并使其更可靠。需要更多研究将这些物质纳入治疗方案并用于疾病治疗。

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