Lv Jie-Li, Li Zhen-Zhen, Zhang Lai-Bin
a School of Pharmacy , Xinxiang Medical University , Xinxiang , People's Republic of China.
Nat Prod Res. 2018 Mar;32(6):632-639. doi: 10.1080/14786419.2017.1332603. Epub 2017 May 25.
A new flavone glycoside, eupatilin 7-O-β-d-glucopyranoside (1) and a new flavone, 5,6,2',4'-tetrahydroxy-7,5'-dimethoxyflavone (2), were isolated from Artemisia argyi. Their structures were unambiguously elucidated by extensive spectroscopic analysis. Both flavonoids were evaluated for in vitro anticoagulation activities. Compound 1 significantly extended thrombin time. Compound 2 had obvious effect in increasing prothrombin time.
从艾蒿中分离出一种新的黄酮苷，灯盏乙素7 - O -β - d -吡喃葡萄糖苷（1）和一种新的黄酮，5,6,2',4'-四羟基-7,5'-二甲氧基黄酮（2）。通过广泛的光谱分析明确阐明了它们的结构。对这两种黄酮类化合物进行了体外抗凝活性评估。化合物1显著延长凝血酶时间。化合物2对增加凝血酶原时间有明显作用。
